Evidence map›Paper›PMID 27815422›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2016

Mucosal and Systemic γδ+ T Cells Associated with Control of Simian Immunodeficiency Virus Infection.

Iskra Tuero, David Venzon, Marjorie Robert-Guroff

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. What Can Gamma Delta T Cells Contribute to an HIV Cure?Frontiers in cellular and infection microbiology · 2020
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Vγ4Frontiers in immunology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Iskra TueroImmune Biology of Retroviral Infection Section, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; and.
David VenzonBiostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Marjorie Robert-GuroffImmune Biology of Retroviral Infection Section, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; and guroffm@mail.nih.gov.
National Institutes of Health · USNational Cancer Institute · US

Funding

Office of Collaborative BiostatisticsZIDSC007202 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI CHOO-WOSOBA, HYOYOUNG · 2009 to 2025
$14.5M
HUMORAL AND CELLULAR IMMUNE RESPONSES TO HUMAN AND NONHUMAN PRIMATE RETROVIRUSESZ01BC005536 · NCI · BASIC SCIENCES · PI ROBERT-GUROFF, MARJORIE · 1996 to 2007
$4.1M
Intramural NIH HHS Z01 BC005536
6 · The paper itself

Abstract

γδ T cells act as a first line of defense against invading pathogens. However, despite their abundance in mucosal tissue, little information is available about their functionality in this compartment in the context of HIV/SIV infection. In this study, we evaluated the frequency, phenotype, and functionality of Vδ1 and Vδ2 T cells from blood, rectum, and the female reproductive tract (FRT) of rhesus macaques to determine whether these cells contribute to control of SIV infection. No alteration in the peripheral Vδ1/Vδ2 ratio in SIV-infected macaques was observed. However, CD8

Indexed as

AnimalsBlood CirculationCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCommunicable Disease ControlCytotoxicity, ImmunologicFemaleGenitalia, FemaleHIV InfectionsHumansImmunity, MucosalInterferon-gammaLymphocyte ActivationMacaca mulattaMaleMucous MembraneInterferon-gammaReceptors, Antigen, T-Cell, gamma-deltaT-cell receptor Vdelta2, human

Identifiers

PMID27815422
PMCPMC5136305
OpenAlexW2547390532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.