Evidence map›Paper›PMID 27815406›Full record

Observational studyNeurology2016

Estimating risk of word-finding problems in adults undergoing epilepsy surgery.

Robyn M Busch, Darlene P Floden, Brigid Prayson, Jessica S Chapin, Kevin H Kim, Lisa Ferguson, William Bingaman, Imad M Najm

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Robyn M BuschFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA. buschr@ccf.org.
Darlene P FlodenFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA.
Brigid PraysonFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA.
Jessica S ChapinFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA.
Kevin H KimFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA.
Lisa FergusonFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA.
William BingamanFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA.
Imad M NajmFrom the Epilepsy Center (R.M.B., W.B., I.M.N., L.F.), Department of Psychiatry & Psychology (R.M.B., D.P.F., L.F.), and Center for Neurological Restoration (D.P.F.), Neurological Institute, Cleveland Clinic, OH; Wellesley College (B.P.), MA; Behavioral Health Services (J.S.C.), Aurora Health Care, Grafton, WI; and Department of Psychology in Education (K.H.K.), University of Pittsburgh, PA.
Aurora Health Care · USBehavioral Health Services · US

Funding

Neurophysiology of response inhibition in PDK23NS091344 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI FLODEN, DARLENE · 2015 to 2019
$843k
NINDS NIH HHS K23 NS091344
6 · The paper itself

Abstract

objectiveThis retrospective, observational study examined the frequency and magnitude of change in naming ability as a function of side/site of epilepsy surgery and identified predictive factors to assist clinicians in identifying patients at low, moderate, or high risk of postoperative naming decline.

methodsA total of 875 adults with pharmacoresistant epilepsy (454 left/421 right; 763 temporal/87 frontal/25 posterior quadrant) met inclusion criteria and completed the Boston Naming Test before and after surgery. Clinically meaningful change in naming ability was assessed using reliable change indices for epilepsy. Demographic, cognitive, and seizure variables were examined to determine factors most predictive of naming decline and to develop a decision tree to assist with clinical decision-making.

resultsNaming decline was rare in right-sided resections and did not exceed the level expected by chance (5% overall; 90% confidence interval [CI] ± 2%). Naming decline occurred in 41% (CI ± 5%) of patients after left temporal resection (TLR) compared to 10%-12% (CI ± 10%-19%) in other left-sided surgical groups. A sizable proportion of left TLR patients (17%; CI ± 4%) showed substantial declines in naming (>11 points). Decline following left TLR was related to later age at seizure onset, older age at surgery, and higher preoperative naming ability. These factors correctly predicted naming decline in 68% of patients and were associated with degree of decline following left TLR. A decision tree is provided to assist clinicians in identifying patients at low, moderate, or high risk for postoperative naming declines.

conclusionsIn addition to discussions regarding risk for memory decline following left TLR, patients should be counseled about potential decline in word-finding ability.

Indexed as

AdolescentAdultAgedBrainDrug Resistant EpilepsyFemaleHumansLanguage DisordersLanguage TestsMaleMiddle AgedNeuropsychological TestsNeurosurgical ProceduresPrognosisRegistriesRetrospective Studies

Identifiers

PMID27815406
PMCPMC5135025
OpenAlexW2548394833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.