Evidence map›Paper›PMID 27815070›Full record

ArticleBiochemical and biophysical research communications2016

Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles.

Tengfei Bian, Joseph M Autry, Denise Casemore, Ji Li, David D Thomas, Gaohong He, Chengguo Xing

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemical and biophysical research communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Isolation of the Sarcoplasmic Reticulum CaMethods and protocols · 2023
    Article
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Tengfei BianDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota, 2231 6th St SE, Minneapolis, MN 55455, United States; State Key Laboratory of Fine Chemicals, R&D Center of Membrane Science and Technology, Dalian University of Technology, Dalian 116024, China.
Joseph M AutryDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, 321 Church St SE, Minneapolis, MN 55455, United States; Biophysical Technology Center, Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, 321 Church St SE, Minneapolis, MN 55455, United States.
Denise CasemoreDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota, 2231 6th St SE, Minneapolis, MN 55455, United States.
Ji LiDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, 321 Church St SE, Minneapolis, MN 55455, United States; Biophysical Technology Center, Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, 321 Church St SE, Minneapolis, MN 55455, United States.
David D ThomasDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, 321 Church St SE, Minneapolis, MN 55455, United States.
Gaohong HeState Key Laboratory of Fine Chemicals, R&D Center of Membrane Science and Technology, Dalian University of Technology, Dalian 116024, China.
Chengguo XingDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota, 2231 6th St SE, Minneapolis, MN 55455, United States. Electronic address: chengguoxing@cop.ufl.edu.
University of Minnesota · USDalian University of Technology · CN

Funding

Structural Dynamics of Muscle Calcium ATPase RegulationR01GM027906 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI THOMAS, DAVID D · 1985 to 2016
$8.6M
Calcium Pump Activators for Heart Failure TherapyR01HL129814 · NHLBI · UNIVERSITY OF MINNESOTA · PI THOMAS, DAVID D · 2015 to 2018
$3.2M
Mechanisms of Anticancer Agents Selective against Drug Resistant LeukemiaR01CA163864 · NCI · UNIVERSITY OF MINNESOTA · PI XING, CHENGGUO · 2012 to 2016
$1.5M
NCI NIH HHS R01 CA163864NHLBI NIH HHS R01 HL129814NIGMS NIH HHS R01 GM027906
6 · The paper itself

Abstract

We have developed a charge-mediated fusion method to reconstitute the sarco/endoplasmic reticulum Ca

Indexed as

AnimalsCalciumIon TransportLipidsMicroscopy, FluorescenceOleic AcidsPhosphatidylcholinesRabbitsSarcoplasmic Reticulum Calcium-Transporting ATPasesSmall Molecule LibrariesStatic ElectricityThapsigarginUnilamellar LiposomesCalciumLipidso-ethyldioleoylphosphatidylcholiniumOleic AcidsPhosphatidylcholinesSarcoplasmic Reticulum Calcium-Transporting ATPasesSmall Molecule LibrariesThapsigarginUnilamellar LiposomesBiomimetic membraneCalcium regulationDrug discoveryElectrostatic fusionLipid reconstitutionTransport proteins

Identifiers

PMID27815070
PMCPMC5123963
OpenAlexW2548318386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.