Evidence map›Paper›PMID 27814939›Full record

ArticleBiologicals : journal of the International Association of Biological Standardization2017

Validation of high throughput screening of human sera for detection of anti-PA IgG by Enzyme-Linked Immunosorbent Assay (ELISA) as an emergency response to an anthrax incident.

Vera A Semenova, Evelene Steward-Clark, Panagiotis Maniatis, Monica Epperson, Amit Sabnis, Jarad Schiffer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biologicals : journal of the International Association of Biological Standardization, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Detection and Identification ofMicroorganisms · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vera A SemenovaCenters for Disease Control and Prevention (CDC), 1600 Clifton Rd., Atlanta, GA 30329, USA. Electronic address: vsemenova@cdc.gov.
Evelene Steward-ClarkCenters for Disease Control and Prevention (CDC), 1600 Clifton Rd., Atlanta, GA 30329, USA.
Panagiotis ManiatisCenters for Disease Control and Prevention (CDC), 1600 Clifton Rd., Atlanta, GA 30329, USA.
Monica EppersonCenters for Disease Control and Prevention (CDC), 1600 Clifton Rd., Atlanta, GA 30329, USA.
Amit SabnisCenters for Disease Control and Prevention (CDC), 1600 Clifton Rd., Atlanta, GA 30329, USA.
Jarad SchifferCenters for Disease Control and Prevention (CDC), 1600 Clifton Rd., Atlanta, GA 30329, USA.
Centers for Disease Control and Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

To improve surge testing capability for a response to a release of Bacillus anthracis, the CDC anti-Protective Antigen (PA) IgG Enzyme-Linked Immunosorbent Assay (ELISA) was re-designed into a high throughput screening format. The following assay performance parameters were evaluated: goodness of fit (measured as the mean reference standard r

Indexed as

AnthraxAntibodies, BacterialAntigens, BacterialBacterial ToxinsEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin GMaleanthrax toxinAntibodies, BacterialAntigens, BacterialBacterial ToxinsImmunoglobulin GAnthraxEmergency responseHuman seraScreeningValidation

Identifiers

PMID27814939
PMCPMC5737902
OpenAlexW2546493607

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.