SynthesisReproductive biology and endocrinology : RB&E2016
Risk of adverse pregnancy and perinatal outcomes after high technology infertility treatment: a comprehensive systematic review.
Synthesis in Reproductive biology and endocrinology : RB&E, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Obstetric Characteristics and Outcomes of Gestational Carrier Pregnancies: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Maternal and perinatal outcomes in twin pregnancies following assisted reproduction: a systematic review and meta-analysis involving 802 462 pregnancies.Human reproduction update · 2024Pooled it
- Miscarriage on Endometriosis and Adenomyosis in Women by Assisted Reproductive Technology or with Spontaneous Conception: A Systematic Review and Meta-Analysis.BioMed research international · 2020Pooled it
- Pooled it
- How safe is the treatment of pregnant women with fear of childbirth using eye movement desensitization and reprocessing therapy? Obstetric outcomes of a multi-center randomized controlled trial.Acta obstetricia et gynecologica Scandinavica · 2023Trial
- Epigenetic, environmental, and sex-specific programming of long-term health in Assisted Reproductive Technologies-conceived offspring†.Biology of reproduction · 2026Review
- Impact of Work-Related Stressors on Pregnancy Outcomes of Cardiologists and Cardiovascular Team Members: It Is Complicated.JACC. Advances · 2026Article
- Association between assisted reproductive technology and gestational diabetes mellitus: the role of serum folate and triglycerides.Nutrition & diabetes · 2026Observational
- Modest increase in the de novo single-nucleotide mutation rate in house mice born by assisted reproduction.Genome research · 2026Article
- Targeted Regulation of Abortion Providers Laws and Pregnancies Conceived Through Fertility Treatment.JAMA health forum · 2026Article
- Perinatal outcomes in pregnancies with very and extremely advanced maternal age: An Italian multicenter retrospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- The effect of TPOAb on pregnancy outcomes among people with polycystic ovary syndrome with euthyroidism undergoing in vitro fertilization.Communications medicine · 2025Article
- Risk factors for gestational diabetes mellitus and postpartum glucose intolerance: a retrospective study from a hospital specializing in infertility treatment.Scientific reports · 2025Article
- The Association Between Infertility Treatment and Birth Outcomes for Nulliparous Persons Who Gave Birth 35 Years and Older: Findings from 2022 National Vital Statistics System Natality Data.Maternal and child health journal · 2025Article
- Pregnancy urinary phenol biomarker concentrations in relation to serum levels of inflammatory cytokines: Results from the EARTH study.Environment international · 2025Article
- Increased rate ofbioRxiv : the preprint server for biology · 2025Article
- The effect of post-thaw culture duration on singleton birthweight resulting from frozen embryo transfer cycles.Archives of medical science : AMS · 2025Article
- Review
- Investigating the Causes of Neonatal Mortality: An Umbrella Review.Iranian journal of public health · 2024Review
- Third-Stage Complications Among In Vitro Fertilization Pregnancies: An Observational Study.Cureus · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the literature, there is growing evidence that subfertile patients who conceived after infertility treatments have an increased risk of pregnancy and perinatal complications and this is particularly true for patients who conceived through use of high technology infertility treatments. Moreover, high technology infertility treatments include many concomitant clinical and biological risk factors. This review aims to summarize in a systematic fashion the current evidence regarding the relative effect of the different procedures for high technology infertility treatments on the risk of adverse pregnancy and perinatal outcome. A literature search up to August 2016 was performed in IBSS, SocINDEX, Institute for Scientific Information, PubMed, Web of Science and Google Scholar and an evidence-based hierarchy was used to determine which articles to include and analyze. Data on prepregnancy maternal factors, low technology interventions, specific procedures for male factor, ovarian tissue/ovary and uterus transplantation, and chromosomal abnormalities and malformations of the offspring were excluded. The available evidences were analyzed assessing the level and the quality of evidence according to the Oxford Centre for Evidence-Based Medicine guidelines and the Grading of Recommendations Assessment, Development, and Evaluation system, respectively. Current review highlights that every single procedure of high technology infertility treatments can play a crucial role in increasing the risk of pregnancy and perinatal complications. Due to the suboptimal level and quality of the current evidence, further well-designed studies are needed.
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