ArticleBMC medicine2016
Maternal urinary metabolic signatures of fetal growth and associated clinical and environmental factors in the INMA study.
Article in BMC medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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Who cites it
27 citing papers in PubMed, 49 citations in OpenAlex.
- Plasma amino acids in early pregnancy and fetal growth trajectories across pregnancy: findings from a multi-racial U.S. pregnancy cohort.European journal of nutrition · 2026Observational
- Dysregulated maternal and newborn fatty acid, sugar and amino acid metabolism associated with high birth weight.International journal of obesity (2005) · 2025Article
- Metabolic alterations in the umbilical cord blood of pregnant women with uncontrolled type 2 diabetes mellitus: a matched-case comparative study in metabolomics.Diabetology & metabolic syndrome · 2025Article
- Article
- Correlation between newborn weight and serum BCAAs in pregnant women with diabetes.Nutrition & diabetes · 2024Article
- Ambient air pollution and adverse birth outcomes: A review of underlying mechanisms.BJOG : an international journal of obstetrics and gynaecology · 2024Review
- Metabolomics to Understand Alterations Induced by Physical Activity during Pregnancy.Metabolites · 2023Review
- Associations of maternal and infant metabolite profiles with foetal growth and the odds of adverse birth outcomes.Pediatric obesity · 2022Article
- Gestational Dating by Urine Metabolic Profile at High Resolution Weekly Sampling Timepoints: Discovery and Validation.Frontiers in molecular medicine · 2022Article
- Non-linear and non-additive associations between the pregnancy metabolome and birthweight.Environment international · 2021Article
- Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview.Environmental epidemiology (Philadelphia, Pa.) · 2021Review
- Global metabolomic profiling reveals hepatic biosignatures that reflect the unique metabolic needs of late-term mother and fetus.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Maternal Metabolome in Pregnancy and Childhood Asthma or Recurrent Wheeze in the Vitamin D Antenatal Asthma Reduction Trial.Metabolites · 2021Article
- Article
- Metabolic Signatures of the Exposome-Quantifying the Impact of Exposure to Environmental Chemicals on Human Health.Metabolites · 2020Review
- Untargeted Metabolomics Screen of Mid-pregnancy Maternal Serum and Autism in Offspring.Autism research : official journal of the International Society for Autism Research · 2020Article
- Maternal plasma metabolic markers of neonatal adiposity and associated maternal characteristics: The GUSTO study.Scientific reports · 2020Article
- Systematic Isolation and Structure Elucidation of Urinary Metabolites Optimized for the Analytical-Scale Molecular Profiling Laboratory.Analytical chemistry · 2019Article
- Gestational route to healthy birth (GaRBH): protocol for an Indian prospective cohort study.BMJ open · 2019Article
- Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries.Diabetologia · 2019Observational
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundMaternal metabolism during pregnancy is a major determinant of the intra-uterine environment and fetal outcomes. Herein, we characterize the maternal urinary metabolome throughout pregnancy to identify maternal metabolic signatures of fetal growth in two subcohorts and explain potential sources of variation in metabolic profiles based on lifestyle and clinical data.
methodsWe used
resultsA metabolic shift between the first and third trimesters of gestation was characterized by
conclusionsSignificant reproducible maternal urinary metabolic signatures of fetal growth and birth weight are identified for the first time and linked to modifiable lifestyle factors. This novel approach to prenatal screening, combining multiple risk factors, present a great opportunity to personalize pregnancy management and reduce newborn disease risk in later life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.