ArticleBMC complementary and alternative medicine2016
The hepatoprotective activity of olive oil and Nigella sativa oil against CCl
Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- Effect ofTheScientificWorldJournal · 2020Pooled it
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- Anti-inflammatory, wound healing, and hepatoprotective effects of Acampe papillosa (Lindl.) Lindl. seed in wistar rats: insights from biochemical, histopathological, and in silico investigations.Journal of molecular histology · 2026Article
- Evening Primrose Oil Attenuates Liver Injury Induced by Carbon Tetrachloride in Albino Rats Via Improvement of Oxidative Stress and TNF-α: Protective Study.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Exploring the Potential Role of Quercetin Dihydrate Against Carbon Tetrachloride Induced Oxidative Stress in Mice: A Randomized Control Trial.Food science & nutrition · 2025Article
- Harnessing the Hepatoprotective and Nephroprotective Potential ofPharmaceuticals (Basel, Switzerland) · 2025Article
- The hepatoprotective effects of the polyphenol-enriched n-butanol fraction ofToxicology reports · 2025Article
- Mini review of plant products as food supplement against MSG-induced liver injury: antioxidant, oxidative stress and histological prospects.Frontiers in pharmacology · 2025Review
- A Review on Nanotechnologically Derived Phytomedicines for the Treatment of Hepatocellular Carcinoma: Recent Advances in Molecular Mechanism and Drug Targeting.Current drug targets · 2025Review
- Protective effect ofToxicology reports · 2024Article
- Olive oil protects against cardiac hypertrophy in D-galactose induced aging rats.BMC cardiovascular disorders · 2024Article
- Comparative effect of olive oil and flaxseed oil on drug induced hepatotoxicity in rats.Food science & nutrition · 2024Article
- The Hepatoprotective Effect of Two Date Palm Fruit Cultivars' Extracts: Green Optimization of the Extraction Process.Foods (Basel, Switzerland) · 2023Article
- The significance of thymoquinone administration on liver toxicity of diazinon and cholinesterase activity; a recommendation for prophylaxis among individuals at risk.BMC complementary medicine and therapies · 2022Article
- Enhancement of the Protective Activity of Vanillic Acid against Tetrachloro-Carbon (CClMolecules (Basel, Switzerland) · 2022Article
- Arabica coffee and olive oils mitigate malathion-induced nephrotoxicity in ratSaudi journal of biological sciences · 2022Article
- Anticancer effect of selenium/chitosan/polyethylene glycol/allyl isothiocyanate nanocomposites against diethylnitrosamine-induced liver cancer in rats.Saudi journal of biological sciences · 2022Article
- Effect of Black Cumin Ethanolic Extract Administration to Superoxide Dismutase and Malondialdehyde in Inhibiting Endothelial Dysfunction in Cigarette Exposed Rats.ARYA atherosclerosis · 2022Article
- Protective Effects of Naringenin fromNutrients · 2022Article
- Effect of silymarin on blood coagulation profile and osmotic fragility in carbon tetrachloride induced hepatotoxicity in male Wistar rats.Toxicology reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLiver disease is the major cause of serious health problem leading to morbidity and mortality worldwide and the problem has increased in search for hepatotherapeutic agents from plants. The present study was designed to compare the probable hepatoprotective activity of olive oil and N. sativa oil on CCl
methodsForty males of a new model of albino rats (Wistar strain) (175-205 g) were divided into four groups. The 1st Group (G1) was the negative control group, the remaining rats were injected with CCl
resultsThe positive control group showed an increase in hepatic enzymes, total bilirubin, creatinine, uric acid, lipid peroxide total cholesterol, triglyceride, low density lipoprotein, very low density lipoproteins, interleukin-6, and a decrease in antioxidant enzymes, high density lipoprotein cholesterol, a decrease in total protein and albumin an when compared with negative control group. Histology of the CCl
conclusionThis study revealed that olive oil and N. sativa oil have a protective effect against CCl
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Registered trials
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