Evidence map›Paper›PMID 27814654›Full record

ReviewFrontiers in bioscience (Landmark edition)2017

A reciprocal HLA-Disease Association in Rheumatoid Arthritis and Pemphigus Vulgaris.

Vincent Van Drongelen, Joseph Holoshitz

Open access · greenAbstract readReview
In one paragraph

Review in Frontiers in bioscience (Landmark edition), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. HLA-G and the MHC Cusp Theory.Frontiers in immunology · 2022
    Review
  3. Article
  4. Article
  5. The Genetics of Pemphigus Vulgaris.Frontiers in medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vincent Van DrongelenDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Joseph HoloshitzUniversity of Michigan, 5520D MSRB1, SPC 5680, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5680, jholo@umich.edu.
University of Michigan · US

Funding

Immune Modulating HLA-Coded Ligands in Rheumatoid ArthritisR01AR059085 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOLOSHITZ, JOSEPH · 2011 to 2020
$3.8M
Class II MHC Allele-Specific Signaling: A New Paradigm in Disease PathogenesisR01GM088560 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOLOSHITZ, JOSEPH · 2009 to 2012
$1.2M
A novel mechanism of gene-environment interaction in autoimmune arthritisR21ES024428 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOLOSHITZ, JOSEPH · 2014 to 2015
$427k
NIAMS NIH HHS R01 AR059085NIEHS NIH HHS R21 ES024428NIGMS NIH HHS R01 GM088560
6 · The paper itself

Abstract

Human leukocyte antigens (HLA) have been extensively studied as being antigen presenting receptors, but many aspects of their function remain elusive, especially their association with various autoimmune diseases. Here we discuss an illustrative case of the reciprocal relationship between certain

Indexed as

HLA AntigensAnimalsArthritis, RheumatoidB-LymphocytesDesmoglein 3Disease Models, AnimalHLA-DRB1 ChainsHumansImmunogenetic PhenomenaMicePemphigusT-LymphocytesDesmoglein 3DSG3 protein, humanHLA AntigensHLA-DRB1*04:02 antigenHLA-DRB1 Chains

Identifiers

PMID27814654
PMCPMC5517013
OpenAlexW2547403448

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.