Evidence map›Paper›PMID 27814470›Full record

ArticleEuropean journal of cancer (Oxford, England : 1990)2016

Birth weight and risk of paediatric Hodgkin lymphoma: Findings from a population-based record linkage study in California.

Corey Triebwasser, Rong Wang, Andrew T DeWan, Catherine Metayer, Libby Morimoto, Joseph L Wiemels, Nina Kadan-Lottick, Xiaomei Ma

Open access · greenAbstract read
In one paragraph

Article in European journal of cancer (Oxford, England : 1990), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Hispanic Ethnicity Differences in Birth Characteristics, Maternal Birthplace, and Risk of Early-Onset Hodgkin Lymphoma: A Population-Based Case-Control Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Corey TriebwasserDepartment of Chronic Disease Epidemiology, Yale School of Public Health, USA.
Rong WangDepartment of Chronic Disease Epidemiology, Yale School of Public Health, USA.
Andrew T DeWanDepartment of Chronic Disease Epidemiology, Yale School of Public Health, USA.
Catherine MetayerDivision of Epidemiology, School of Public Health, University of California, Berkeley, USA.
Libby MorimotoDivision of Epidemiology, School of Public Health, University of California, Berkeley, USA.
Joseph L WiemelsDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Nina Kadan-LottickSection of Pediatric Hematology/Oncology, Yale School of Medicine, USA; Yale Comprehensive Cancer Center, Yale School of Medicine, USA.
Xiaomei MaDepartment of Chronic Disease Epidemiology, Yale School of Public Health, USA; Yale Comprehensive Cancer Center, Yale School of Medicine, USA. Electronic address: xiaomei.ma@yale.edu.
Yale University · USUniversity of California, Berkeley · USUniversity of California, San Francisco · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
Training Program in Translational Brain Tumor ResearchT32CA151022 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joseph F Costello · 2010 to 2026
$6.6M
Genome-Wide Association Study of Childhood Leukemia by Hispanic StatusR01CA155461 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MA, XIAOMEI, WIEMELS, JOSEPH LEO · 2011 to 2014
$4.1M
Project 3: Prenatal Exposure, DNA Methylation & Childhood LeukemiaP01ES018172 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 2009 to 2013
$3.7M
Perinatal immune development and risk of childhood acute lymphoblastic leukemiaR01CA175737 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MA, XIAOMEI, WIEMELS, JOSEPH LEO · 2014 to 2018
$3.0M
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001863NCCDPHP CDC HHS U58 DP003862NCI NIH HHS HHSN261201000034CNCI NIH HHS HHSN261201000035CNCI NIH HHS HHSN261201000035INCI NIH HHS HHSN261201000140CNCI NIH HHS R01 CA155461NCI NIH HHS R01 CA175737NCI NIH HHS T32 CA151022NIEHS NIH HHS P01 ES018172
6 · The paper itself

Abstract

objectiveTo evaluate the relationship between birth weight (along with a variety of pre and perinatal characteristics) and the risk of paediatric Hodgkin lymphoma (HL) diagnosed at age <20 years.

methodWe linked California statewide birth records from 1978-2009 and cancer diagnosis data from 1988-2011 to conduct a population-based case-control study with 1216 cases and 4485 controls (matched on birth month and year, sex, and race/ethnicity). Conditional logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI) of paediatric HL overall and by age of diagnosis, controlling for other perinatal factors.

resultsCompared to children with a normal birth weight (2500-3999 g), those who had a high birth weight (≥4000 g) had an increased risk of paediatric HL overall (OR = 1.23, 95% CI: 1.02-1.48) after adjusting for birth order, maternal age at the time of delivery, and paternal age at the time of delivery. The magnitude of association appeared larger for subgroups of children whose age of diagnosis was 0-10 years (OR = 1.56, 95% CI: 1.04-2.24) or 15-19 years (OR = 1.43, 95% CI: 1.11-1.83), while no association was observed in 11-14 year olds. Compared with firstborn children, those who were third or higher in birth order had a reduced risk of paediatric HL overall (OR = 0.80, 95% CI: 0.67-0.95), and this association also varied by age of diagnosis.

conclusionsIn this study with the largest number of paediatric HL cases, high birth weight was associated with an increased disease risk for most but not all ages of diagnosis. The different findings by age of diagnosis regarding both birth weight and birth order underscore the importance to stratify paediatric HL by age at diagnosis in future etiological investigations.

Indexed as

Birth WeightAdolescentAge of OnsetBirth OrderCaliforniaCase-Control StudiesChildChild, PreschoolEthnicityFemaleFetal MacrosomiaHodgkin DiseaseHumansInfantInfant, Low Birth WeightInfant, NewbornBirth orderBirth weightCase–control studyHodgkin lymphomaPaediatric cancer

Identifiers

PMID27814470
PMCPMC5125877
OpenAlexW2546911826

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.