Evidence map›Paper›PMID 27813450›Full record

ArticleThe journal of spinal cord medicine2017

Exploring daily blood pressure fluctuations and cardiovascular risk among individuals with motor complete spinal cord injury: a pilot study.

Derry L Dance, Amit Chopra, Kent Campbell, David S Ditor, Magdy Hassouna, B Catharine Craven

Abstract read
In one paragraph

Article in The journal of spinal cord medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Correlating autonomic physiology with symptoms of autonomic dysreflexia after spinal cord injury.PM & R : the journal of injury, function, and rehabilitation · 2025
    Article
  5. Article
  6. Responses to Valsalva's maneuver in spinal cord injury do not broadly relate to vasoconstrictor capacity.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
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  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Derry L Dancea Department of Medicine , University of Toronto , Toronto , ON , Canada.
Amit Choprab Toronto Rehabilitation Institute , University Health Network , Toronto , ON , Canada.
Kent Campbelld Dalla Lana School of Public Health , University of Toronto , Toronto , ON , Canada.ORCID 0000-0002-9755-0249
David S Ditore Department of Physical Education and Kinesiology , Brock University , St. Catharines , ON , Canada.
Magdy Hassounab Toronto Rehabilitation Institute , University Health Network , Toronto , ON , Canada.ORCID 0000-0002-1096-3391
B Catharine Cravena Department of Medicine , University of Toronto , Toronto , ON , Canada.
University Health Network · CABrock University · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinically silent autonomic dysfunction with bowel and bladder care, are postulated to contribute to cardiovascular disease after chronic spinal cord injury (SCI).

objectiveWe describe the frequency and severity of dysreflexic episodes, termed transient blood pressure elevations (T-BPE) over 48 hours in adults with cervical or high-thoracic motor-complete SCI.

settingTertiary SCI Rehabilitation Centre in Toronto, Canada.

participantsIndividuals with chronic SCI, C1-T3 AIS A or B, >1 year post-injury, living in the community (n=19). OUTCOME MEASURES: Data were obtained via 48-hour ambulatory blood pressure (BP) and heart rate (HR) monitoring, with data captured at 10-minute intervals and a concurrent diary describing activities of daily living, and bladder/bowel routines. T-BPE were defined as a ≥ 40 mmHg elevation in systolic blood pressure (SBP) above the participant's supine baseline. Severe (≥ 60-79 mmHg) and Extreme ≥80 mmHg elevations in SBP were described.

resultsThirteen participants experienced T-BPE within the assessment period, with 7/13 experiencing "severe", and 3/13 experiencing "extreme" SBP elevations. The median number of T-BPE was 8 (IQR = 3), and the mean ± SD SBP during T-BPE was 150 ± 16 mmHg, These T-BPE were verified as dysreflexic events using a conservative definition of a >40 mmHg increase in SBP, with a concurrent 10 bpm decrease in HR, above the 48-hour average SBP, yielding 12/19 participants with T-BPE.

conclusionsT-BPE were frequent, often with severe or extreme elevations in SBP, despite few reported symptoms. Recognition and management of these dysreflexic events associated with T-BPE are needed, which may ameliorate cardiovascular disease risk.

Indexed as

Blood PressureAdultCardiovascular DiseasesHeart RateHumansMaleMiddle AgedPilot ProjectsSpinal Cord InjuriesAutonomic dysreflexiaBlood pressureCardiovascular diseaseSpinal cord injuryTetraplegia

Identifiers

PMID27813450
PMCPMC5537957
OpenAlexW2547545344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.