ArticleHuman brain mapping2017
The functional role of human right hippocampal/parahippocampal theta rhythm in environmental encoding during virtual spatial navigation.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Attention training modulates resting-state neurophysiological abnormalities in posttraumatic stress disorder.Psychiatry research. Neuroimaging · 2018Trial
- Neural synchrony and cognitive map formulation in collaborative navigation: leader-follower couplings revealed by EEG hyperscanning.Cognitive neurodynamics · 2026Article
- Differences in Anatomical Structures and Resting-State Brain Networks Between Elite Wrestlers and Handball Athletes.Brain sciences · 2025Article
- Frequency-specific directed connectivity between the hippocampus and parietal cortex during verbal and spatial episodic memory: an intracranial EEG replication.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Hippocampal-parietal cortex causal directed connectivity during human episodic memory formation: Replication across three experiments.bioRxiv : the preprint server for biology · 2024Article
- Multisensory input modulates memory-guided spatial navigation in humans.Communications biology · 2023Article
- Replicable patterns of causal information flow between hippocampus and prefrontal cortex during spatial navigation and spatial-verbal memory formation.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Task-related connectivity of decision points during spatial navigation in a schematic map.Brain structure & function · 2022Article
- Topologic Reorganization of White Matter Connectivity Networks in Early-Blind Adolescents.Neural plasticity · 2022Article
- Using Posterior EEG Theta Band to Assess the Effects of Architectural Designs on Landmark Recognition in an Urban Setting.Frontiers in human neuroscience · 2020Article
- The Neural Dynamics of Novel Scene Imagery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Altered whole-brain gray matter volume in high myopia patients: a voxel-based morphometry study.Neuroreport · 2018Article
- Veterans with PTSD demonstrate amygdala hyperactivity while viewing threatening faces: A MEG study.Biological psychology · 2018Article
- Non-invasive Investigation of Human Hippocampal Rhythms Using Magnetoencephalography: A Review.Frontiers in neuroscience · 2018Review
- Adolescent Hippocampal and Prefrontal Brain Activation During Performance of the Virtual Morris Water Task.Frontiers in human neuroscience · 2018Article
- BrainWave: A Matlab Toolbox for Beamformer Source Analysis of MEG Data.Frontiers in neuroscience · 2018Article
- Theta band power increases in the posterior hippocampus predict successful episodic memory encoding in humans.Hippocampus · 2017Article
- Resting-State Neurophysiological Abnormalities in Posttraumatic Stress Disorder: A Magnetoencephalography Study.Frontiers in human neuroscience · 2017Article
- Individual differences in theta-band oscillations in a spatial memory network revealed by electroencephalography predict rapid place learning.Brain and neuroscience advancesArticle
- Perceived stress and rejection associated with functional network strength during memory retrieval in adolescents.Cognitive neuroscienceArticle
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Authors and funding
4 authors.
Funding
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Abstract
Low frequency theta band oscillations (4-8 Hz) are thought to provide a timing mechanism for hippocampal place cell firing and to mediate the formation of spatial memory. In rodents, hippocampal theta has been shown to play an important role in encoding a new environment during spatial navigation, but a similar functional role of hippocampal theta in humans has not been firmly established. To investigate this question, we recorded healthy participants' brain responses with a 160-channel whole-head MEG system as they performed two training sets of a virtual Morris water maze task. Environment layouts (except for platform locations) of the two sets were kept constant to measure theta activity during spatial learning in new and familiar environments. In line with previous findings, left hippocampal/parahippocampal theta showed more activation navigating to a hidden platform relative to random swimming. Consistent with our hypothesis, right hippocampal/parahippocampal theta was stronger during the first training set compared to the second one. Notably, theta in this region during the first training set correlated with spatial navigation performance across individuals in both training sets. These results strongly argue for the functional importance of right hippocampal theta in initial encoding of configural properties of an environment during spatial navigation. Our findings provide important evidence that right hippocampal/parahippocampal theta activity is associated with environmental encoding in the human brain. Hum Brain Mapp 38:1347-1361, 2017. © 2016 Wiley Periodicals, Inc.
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