ReviewExperientia supplementum (2012)
The Role of AMPK in Drosophila melanogaster.
Review in Experientia supplementum (2012). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- M1-linked ubiquitination by LUBAC regulates AMPK signalling and the response to energetic stress.Cell death and differentiation · 2026Article
- The "yeast-drop" treatment protocol in theFrontiers in tuberculosis · 2026Article
- Rice stripe mosaic virus M protein antagonizes G-protein-induced antiviral autophagy in insect vectors.PLoS pathogens · 2025Article
- Exploring the multifaceted functions of APPL in metabolism and memory using Drosophila melanogaster.Molecules and cells · 2025Article
- Fine-tuning AMPK in physiology and disease using point-mutant mouse models.Disease models & mechanisms · 2024Review
- Article
- Adenosine Monophosphate-Activated Protein Kinase (AMPK) Phosphorylation Is Required for 20-Hydroxyecdysone Regulates Ecdysis inInternational journal of molecular sciences · 2023Article
- Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models.Nature communications · 2023Article
- Transcriptome and metabolome comprehensive analysis reveal the molecular basis of slow-action and non-repellency of cycloxaprid against an eusocial pest,Frontiers in physiology · 2023Article
- Review
- Metformin Repurposing for Parkinson Disease Therapy: Opportunities and Challenges.International journal of molecular sciences · 2021Review
- AMPK signaling mediates synphilin-1-induced hyperphagia and obesity inJournal of cell science · 2021Article
- Overexpression of Activated AMPK in theGenes · 2021Article
- Transcriptomic and Metabolomic Data Reveal the Key Metabolic Pathways AffectingFrontiers in physiology · 2021Article
- Regulation of growth in Drosophila melanogaster: the roles of mitochondrial metabolism.Journal of biochemistry · 2020Review
- AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance.PLoS genetics · 2018Article
- Control of protein translation by IPFly · 2017Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In the fruit fly, Drosophila melanogaster, mono-allelic expression of AMPK-α, -β, and -γ yields a single heterotrimeric energy sensor that regulates cellular and whole-body energetic homeostasis. The genetic simplicity of Drosophila, with only a single gene for each subunit, makes the fruit fly an appealing organism for elucidating the effects of AMPK mutations on signaling pathways and phenotypes. In addition, Drosophila presents researchers with an opportunity to use straightforward genetic approaches to elucidate metabolic signaling pathways that contain a level of complexity similar to that observed in mammalian pathways. Just as in mammals, however, the regulatory realm of AMPK function extends beyond metabolic rates and lipid metabolism. Indeed, experiments using Drosophila have shown that AMPK may exert protective effects with regard to life span and neurodegeneration. This chapter addresses a few of the research areas in which Drosophila has been used to elucidate the physiological functions of AMPK. In doing so, this chapter provides a primer for basic Drosophila nomenclature, thereby eliminating a communication barrier that persists for AMPK researchers trained in mammalian genetics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.