Evidence map›Paper›PMID 27812790›Full record

ArticleObesity surgery2017

The Role of Sleeve Gastrectomy in Reducing Cardiovascular Risk.

Luciana Tromba, Francesco Tartaglia, Sabino Carbotta, Nadia Sforza, Fabio Pelle, Vanessa Colagiovanni, Giovanni Carbotta, Stefania Cavaiola, Giovanni Casella

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Endothelial Function in Obese Patients Treated with Bariatric Surgery.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Luciana TrombaSurgical Sciences Department, "Sapienza" University of Rome, Rome, Italy.
Francesco TartagliaSurgical Sciences Department, "Sapienza" University of Rome, Rome, Italy. francesco.tartaglia@uniroma1.it.
Sabino CarbottaSurgical Sciences Department, "Sapienza" University of Rome, Rome, Italy.
Nadia SforzaSurgical Sciences Department, "Sapienza" University of Rome, Rome, Italy.
Fabio PelleSurgical Sciences Department, "Sapienza" University of Rome, Rome, Italy.
Vanessa ColagiovanniGynecological, Obstetric Sciences Department and Urological Sciences, "Sapienza" University of Rome, Rome, Italy.
Giovanni CarbottaDepartment of Experimental Medicine, "Sapienza" University of Rome, Rome, Italy.
Stefania CavaiolaCNR, IBB, Rome, Italy.
Giovanni CasellaSurgical Sciences Department, "Sapienza" University of Rome, Rome, Italy.
Sapienza University of Rome · ITInstitute of Molecular Biology and Pathology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is an independent cardiovascular risk factor and a catalyst of other cardiovascular risk factors, such as hypertension, dyslipidemia, type 2 diabetes mellitus (DM2) and metabolic syndrome.

methodsWe analyzed cardiovascular risk in obese patients before and after sleeve gastrectomy (SG). To this end, we studied changes in body mass index (BMI), blood chemistry parameters that characterize the risk of atherosclerosis and instrumental parameters (objective markers of this risk), namely intima-media thickness (IMT) and flow-mediated dilation (FMD), the latter reflecting endothelial function. We also considered purely cardiac parameters-mitral annular plane systolic excursion (MAPSE) and tricuspid annular plane systolic excursion (TAPSE)-which describe cardiac risk more specifically than the ejection fraction. Alteration of one or more of these parameters determines an increase in cardiovascular morbidity and mortality.

resultsThe results showed that weight loss, in patients undergoing SG, is accompanied by a reduced BMI and a marked improvement in blood chemistry, confirming what has already been shown in many other studies, but the most interesting finding was the effect of SG on the instrumental markers of atherosclerosis. In particular, carotid IMT was significantly reduced (p < 0.001) and FMD significantly improved. MAPSE and TAPSE also improved significantly at both follow-up assessments (p < 0.001).

conclusionsThis study suggests that SG should be considered from a broader perspective, i.e. as a weight loss treatment that also improves obesity-related morbidity and mortality, benefitting both the patient and, in an economic sense, the society as a whole.

Indexed as

Bariatric SurgeryAdultAtherosclerosisBody Mass IndexCardiovascular DiseasesCarotid Intima-Media ThicknessDyslipidemiasFemaleGastrectomyHumansHypertensionMaleMiddle AgedObesityObesity, MorbidRisk FactorsBariatric surgeryCardiovascular riskColor Doppler echocardiographyObesitySleeve gastrectomy

Identifiers

PMID27812790
OpenAlexW2547372368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.