Evidence map›Paper›PMID 27812536›Full record

ArticleJournal of lung, pulmonary & respiratory research2016

Rasch Analysis of The WURSS-21 Dimensional Validation and Assessment of Invariance.

Roger L Brown, Chidi N Obasi, Bruce Barrett

Registry-linked trialAbstract read
In one paragraph

Article in Journal of lung, pulmonary & respiratory research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05819190 (Efficacy and Safety of Healsea® Hypertonic Nasal Spray 2.7% in the Treatment of Acute Infectious Rhinitis in Adults), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05819190 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Healsea® Hypertonic Nasal Spray 2.7% in the Treatment of Acute Infectious Rhinitis in Adults

TypeinterventionalSponsorLallemand Pharma AGRan2022 to 2023Enrolled200ConditionsCommon ColdArmsHealsea Rescue*, Placebo
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. The validity of single-item measures of health-related quality of life across groups differing in acute respiratory symptom severity.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roger L BrownUniversity of Wisconsin School of Nursing, Research Design & Statistics Unit.
Chidi N ObasiDepartment of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health.
Bruce BarrettDepartment of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health.

Funding

Placebo: Physician or Pill? RCT in a commom cold modelR01AT001428 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2003 to 2006
$1.2M
Meditation and Exercise for Prevention of Acute Respiratory InfectionR01AT004313 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2009 to 2010
$1.2M
Mentoring and research in patient-oriented medicineK24AT006543 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2012 to 2016
$818k
NCCIH NIH HHS K24 AT006543NCCIH NIH HHS R01 AT001428NCCIH NIH HHS R01 AT004313
6 · The paper itself

Abstract

backgroundThe purpose of this study is to use Rasch analysis to explore the validity of considering self-report scores from Wisconsin Upper Respiratory Symptom Survey (WURSS-21) as a single global illness severity domain. The WURSS-21 is a widely used questionnaire instrument that assesses symptom severity and functional impact of common cold and flu-like illness.

methodsThis study applies item response theory, specifically Rasch modeling, to investigate dimensional and measurement properties of the WURSS-21, and looks at invariance over time. The data assessed represents 1167 people, each scoring the WURSS-21 once daily for up to seven consecutive days of acute upper respiratory infection (URI) illness.

resultsRasch analysis supports a single domain WURSS-21 global symptom score. Assessment of differential item functioning across seven days of illness provides evidence for measurement invariance. While individual items rating physical symptoms were somewhat variable, items rating functional impairment and quality of life impact appeared quite consistent across a single domain over seven days of illness.

conclusionRasch analysis of WURSS-21 items provides evidential support for a single invariant domain. These findings support the practice of using a simply summed daily global illness severity score to represent the overall symptomatic and functional impairments arising from URI.

Indexed as

Common coldPatient reported outcomesQuality of lifeURIValidation

Identifiers

PMID27812536
PMCPMC5089813

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.