Evidence map›Paper›PMID 27812318›Full record

ArticleFrontiers in neuroscience2016

Neural Correlates of Auditory Perceptual Awareness and Release from Informational Masking Recorded Directly from Human Cortex: A Case Study.

Andrew R Dykstra, Eric Halgren, Alexander Gutschalk, Emad N Eskandar, Sydney S Cash

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
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  4. Association of Bidirectional Network Cores in the Brain with Perceptual Awareness and Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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  14. Review
  15. A roadmap for the study of conscious audition and its neural basis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Andrew R DykstraProgram in Speech and Hearing Bioscience and Technology, Harvard-MIT Division of Health Sciences and TechnologyCambridge, MA, USA; Department of Neurology, Massachusetts General Hospital and Harvard Medical SchoolBoston, MA, USA.
Eric HalgrenDepartments of Radiology and Neurosciences, University of California San Diego, La Jolla, CA, USA.
Alexander GutschalkDepartment of Neurology, Ruprecht-Karls-Universität Heidelberg Heidelberg, Germany.
Emad N EskandarDepartment of Neurosurgery, Massachusetts General Hospital and Harvard Medical School Boston, MA, USA.
Sydney S CashDepartment of Neurology, Massachusetts General Hospital and Harvard Medical School Boston, MA, USA.
Harvard University · USHarvard–MIT Division of Health Sciences and Technology · USHeidelberg University · DEUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In complex acoustic environments, even salient supra-threshold sounds sometimes go unperceived, a phenomenon known as informational masking. The neural basis of informational masking (and its release) has not been well-characterized, particularly outside auditory cortex. We combined electrocorticography in a neurosurgical patient undergoing invasive epilepsy monitoring with trial-by-trial perceptual reports of isochronous target-tone streams embedded in random multi-tone maskers. Awareness of such masker-embedded target streams was associated with a focal negativity between 100 and 200 ms and high-gamma activity (HGA) between 50 and 250 ms (both in auditory cortex on the posterolateral superior temporal gyrus) as well as a broad P3b-like potential (between ~300 and 600 ms) with generators in ventrolateral frontal and lateral temporal cortex. Unperceived target tones elicited drastically reduced versions of such responses, if at all. While it remains unclear whether these responses reflect conscious perception, itself, as opposed to pre- or post-perceptual processing, the results suggest that conscious perception of target sounds in complex listening environments may engage diverse neural mechanisms in distributed brain areas.

Indexed as

auditory cortexconscious perceptionelectrocorticographyhigh-gamma activityinformational masking

Identifiers

PMID27812318
PMCPMC5071374
OpenAlexW2533685684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.