ReviewPLoS pathogens2016
The Strange Lifestyle of Multipartite Viruses.
Review in PLoS pathogens, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed.
- Small impact of the host plant physiological state on the genome formula of a nanovirus.PLoS pathogens · 2026Article
- Article
- Article
- Intracellular interactions shape antiviral resistance outcomes in poliovirus via eco-evolutionary feedback.Nature ecology & evolution · 2026Article
- Living Together Apart: Quantitative Perspectives on the Costs and Benefits of a Multipartite Genome Organization in Viruses.Viruses · 2025Article
- Intracellular interactions shape antiviral resistance outcomes in poliovirus via eco-evolutionary feedback.bioRxiv : the preprint server for biology · 2025Article
- Phage quest: a beginner's guide to explore viral diversity in the prokaryotic world.Briefings in bioinformatics · 2025Review
- A group of segmented viruses contains genome segments sharing homology with multiple viral taxa.Journal of virology · 2025Article
- Relative frequency dynamics and loading of beet necrotic yellow vein virus genomic RNAs during the acquisition by its vectorJournal of virology · 2025Article
- Aspects of the lifestyle of multipartite viruses apply to monopartite segmented and perhaps nonsegmented viruses.Npj viruses · 2024Review
- Robust Approaches to the Quantitative Analysis of Genome Formula Variation in Multipartite and Segmented Viruses.Viruses · 2024Article
- The genome formula of a multipartite virus is regulated both at the individual segment and the segment group levels.PLoS pathogens · 2024Article
- Evolution of a novel engineered tripartite viral genome of a torradovirus.Virus evolution · 2024Article
- Conserved untranslated regions of multipartite viruses: Natural markers of novel viral genomic components and tags of viral evolution.Virus evolution · 2024Article
- The genome of a bunyavirus cannot be defined at the level of the viral particle but only at the scale of the viral population.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Constant ratio between the genomic components of bipartite begomoviruses during infection and transmission.Virology journal · 2023Article
- Insights into the Differential Composition of Stem-Loop Structures of Nanoviruses and Their Impacts.Microbiology spectrum · 2023Article
- Bipartite genome and structural organization of the parvovirus Acheta domesticus segmented densovirus.Nature communications · 2023Article
- Comparative Genome Analysis of Old World and New World TYLCV Reveals a Biasness toward Highly Variable Amino Acids in Coat Protein.Plants (Basel, Switzerland) · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multipartite viruses have one of the most puzzling genetic organizations found in living organisms. These viruses have several genome segments, each containing only a part of the genetic information, and each individually encapsidated into a separate virus particle. While countless studies on molecular and cellular mechanisms of the infection cycle of multipartite viruses are available, just as for other virus types, very seldom is their lifestyle questioned at the viral system level. Moreover, the rare available "system" studies are purely theoretical, and their predictions on the putative benefit/cost balance of this peculiar genetic organization have not received experimental support. In light of ongoing progresses in general virology, we here challenge the current hypotheses explaining the evolutionary success of multipartite viruses and emphasize their shortcomings. We also discuss alternative ideas and research avenues to be explored in the future in order to solve the long-standing mystery of how viral systems composed of interdependent but physically separated information units can actually be functional.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.