Evidence map›Paper›PMID 27812103›Full record

ArticlePloS one2016

Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU®.

Florian Debus, Rolf Lefering, Philipp Lechler, Tim Schwarting, Benjamin Bockmann, Erwin Strasser, Carsten Mand, Steffen Ruchholtz, Michael Frink, TraumaRegister DGU

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. [Trauma center management].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2021
    Review
  3. Management of multiple traumas in emergency medicine department: A review.Journal of family medicine and primary care · 2019
    Review
  4. Multiple Trauma and Emergency Room Management.Deutsches Arzteblatt international · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Florian DebusDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Gießen and Marburg, Marburg, Germany.
Rolf LeferingInstitute for Research in Operative Medicine (IFOM), University of Witten/Herdecke, Cologne, Germany.
Philipp LechlerDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Gießen and Marburg, Marburg, Germany.
Tim SchwartingDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Gießen and Marburg, Marburg, Germany.
Benjamin BockmannDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Gießen and Marburg, Marburg, Germany.
Erwin StrasserDepartment of Transfusion Medicine and Hemostaseology, University Hospital Erlangen, Erlangen, Germany.
Carsten MandDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Gießen and Marburg, Marburg, Germany.
Steffen RuchholtzDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Gießen and Marburg, Marburg, Germany.
Michael FrinkDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Gießen and Marburg, Marburg, Germany.
TraumaRegister DGU
Universitätsklinikum Gießen und Marburg · DEUniversitätsklinikum Erlangen · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHemorrhagic shock remains one of the most common causes of death in severely injured patients. It is unknown to what extent the presence of a blood bank in a trauma center influences therapy and outcome in such patients. MATERIAL AND

methodsWe retrospectively analyzed prospectively recorded data from the TraumaRegister DGU® and the TraumaNetzwerk DGU®. Inclusion criteria were Injury Severity Score (ISS) ≥ 16, primarily treated patients, and hospital admission 2 years before or after the audit process.

resultsComplete data sets of 18,573 patients were analyzed. Of 457 hospitals included, 33.3% had an in-house blood bank. In trauma centers with a blood bank (HospBB), packed red blood cells (PRBCs) (21.0% vs. 17.4%, p < 0.001) and fresh frozen plasma (FFP) (13.9% vs. 10.2%, p <0.001) were transfused significantly more often than in hospitals without a blood bank (Hosp0). However, no significant difference was found for in-hospital mortality (standard mortality ratio [SMR, 0.907 vs. 0.945; p = 0.25). In patients with clinically apparent shock on admission, no difference of performed transfusions were present between HospBB and Hosp0 (PRBCs, 51.4% vs. 50.4%, p = 0.67; FFP, 32.7% vs. 32.7%, p = 0.99), and no difference in in-hospital mortality was observed (SMR, 0.907 vs. 1.004; p = 0.21). DISCUSSION: In HospBB transfusions were performed more frequently in severely injured patients without positively affecting the 24h mortality or in-house mortality. Easy access may explain a more liberal transfusion concept.

Indexed as

Blood BanksInjury Severity ScoreAdultBlood TransfusionFemaleHumansMaleMiddle AgedPatient AdmissionRetrospective StudiesShock, HemorrhagicTreatment Outcome

Identifiers

PMID27812103
PMCPMC5094683
OpenAlexW2546937998

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.