ArticleScientific reports2016
Effects of chronic noise on glucose metabolism and gut microbiota-host inflammatory homeostasis in rats.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 91 citations in OpenAlex.
- Residential proximity to major roadways and prevalent diabetes in older adults: a cross-sectional study based on CLHLS.BMC geriatrics · 2026Article
- Impact of residential noise pollution on early-onset myocardial infarction risk results from the DECIBEL-MI (Determination of Environmental CIty-noise's Burden, Exposure, and Link to Myocardial Infarction) study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Associations Between Noise-Induced Hearing Loss and the Risk of High Fasting Blood Glucose Among the Air Force Population.Safety and health at work · 2026Article
- Beyond microbial exposure and colonization: multisensory shaping of the gut microbiome.mSystems · 2025Review
- Double-Edged Sword: Urbanization and Response of Amniote Gut Microbiome in the Anthropocene.Microorganisms · 2025Review
- Effects of Long-Term Airport Noise Exposure on Inflammation and Intestinal Flora and Their Metabolites in Mice.Metabolites · 2025Article
- Music of Different Tones Maintains Intestinal Immunity by Regulating the Intestinal Barrier and Intestinal Microbiota.International journal of molecular sciences · 2025Article
- Molecular connections between inflammation and social determinants of health.Frontiers in epidemiology · 2025Review
- Effects of Environmental Noise Stress on Mouse Metabolism.International journal of molecular sciences · 2024Article
- The impact of co-exposure to air and noise pollution on the incidence of metabolic syndrome from a health checkup cohort.Scientific reports · 2024Article
- Health position paper and redox perspectives - Disease burden by transportation noise.Redox biology · 2024Review
- Effects of Music and White Noise Exposure on the Gut Microbiota, Oxidative Stress, and Immune-Related Gene Expression of Mice.Microorganisms · 2023Article
- Application of wearable devices for monitoring cardiometabolic dysfunction under the exposome paradigm.Chronic diseases and translational medicine · 2023Review
- Article
- Treatments and regulatory mechanisms of acoustic stimuli on mood disorders and neurological diseases.Frontiers in neuroscience · 2023Review
- Dysregulations of metabolites and gut microbes and their associations in rats with noise induced hearing loss.Frontiers in microbiology · 2023Article
- Effects of Aqueous Saffron Extract on Glucoregulation as Well as Hepatic Agt and TNF-α Gene Expression in Rats Subjected to Sub-Chronic Stress.Advanced biomedical research · 2023Article
- Changes to the gut microbiota of a wild juvenile passerine in a multidimensional urban mosaic.Scientific reports · 2022Article
- Toxicopathological changes induced by combined exposure to noise and toluene in New Zealand White rabbits.Arhiv za higijenu rada i toksikologiju · 2022Article
- The Embodiment of Insult: A Theory of Biobehavioral Response to Workplace Incivility.Journal of management · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic noise exposure has been implicated in increased risk of diabetes. However, there is limited experimental evidence of the mechanisms linking chronic noise stress and glucose metabolism. We addressed this in the present study by examining glucose metabolism, immune response, and changes in gut microbiota/host inflammatory homeostasis in rats exposed to noise for 30 consecutive days. Chronic noise exposure increased blood glucose and corticosterone levels for at least 14 days after cessation of noise. Stressed rats also exhibited elevated levels of glycogen and triglyceride in the liver and impaired hepatic insulin production via insulin-induced insulin receptor/insulin receptor substrate 1/glycogen synthase kinase 3β signalling, which persisted for 3-14 days after cessation of noise exposure. Chronic noise altered the percentage of Proteobacteria and Actinobacteria in the gut, increasing Roseburia but decreasing Faecalibacterium levels in the cecum relative to controls. Immunoglobulin A, interleukin 1β, and tumor necrosis factor α levels were also elevated in the intestine of these animals, corresponding to noise-induced abnormalities in glucose regulation and insulin sensitivity. These results suggest that lifelong environmental noise exposure could have cumulative effects on diabetes onset and development resulting from alterations in gut microbiota composition and intestinal inflammation.
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