ArticleCell research2016
Codon optimality and mRNA decay.
Article in Cell research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Translational Control in Cardiac Pathophysiology and Therapeutic Development: When mRNA Meets the Heart.International journal of molecular sciences · 2025Review
- mRNA vaccine sequence and structure design and optimization: Advances and challenges.The Journal of biological chemistry · 2025Review
- Quantification of elongation stalls and impact on gene expression in yeast.RNA (New York, N.Y.) · 2023Article
- Quantification of elongation stalls and impact on gene expression in yeast.bioRxiv : the preprint server for biology · 2023Article
- A nascent peptide code for translational control of mRNA stability in human cells.Nature communications · 2022Article
- Genome-wide analysis of lncRNA stability in human.PLoS computational biology · 2021Article
- Pervasive and dynamic transcription initiation inGenome research · 2019Article
- YeasTSS: an integrative web database of yeast transcription start sites.Database : the journal of biological databases and curation · 2019Article
- A Robust and Quantitative Reporter System To Evaluate Noncanonical Amino Acid Incorporation in Yeast.ACS synthetic biology · 2018Article
- Poor codon optimality as a signal to degrade transcripts with frameshifts.Transcription · 2018Article
- The link between adjacent codon pairs and mRNA stability.BMC genomics · 2017Article
- An RNA decay factor wears a new coat: UPF3B modulates translation termination.F1000Research · 2017Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent evidence indicates that codon optimality is a broad determinant of mRNA stability. A study by Radhakrishnan et al. in Cell raises the possibility that the conserved DEAD-box protein Dhh1 underlies the phenomenon.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.