ArticleThe Journal of experimental biology2017
Retinal specialization through spatially varying cell densities and opsin coexpression in cichlid fish.
Article in The Journal of experimental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Opsin gene evolution in aquatic, amphibious and terrestrial blennies (Blenniidae).Biology open · 2026Article
- Graded opsin co-expression along the butterfly retina fine tunes the spectral sensitivity of a colour-opponent cell across the visual field.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Exceptional Visual-Opsin Coexpression and Phenotypic Diversity in Outer-Retinal Photoreceptors of Caenophidian Snakes.The Journal of comparative neurology · 2025Article
- Rapid Divergence of Visual Systems and Signaling Traits to Contrasting Light Regimes During Early Speciation of African Crater Lake Cichlid Fish.Molecular biology and evolution · 2025Article
- Multiple Ecological Axes Drive Molecular Evolution of Cone Opsins in Beloniform Fishes.Journal of molecular evolution · 2024Article
- Ultraviolet vision in anemonefish improves colour discrimination.The Journal of experimental biology · 2024Article
- Development of dim-light vision in the nocturnal reef fish family Holocentridae. I: Retinal gene expression.The Journal of experimental biology · 2022Article
- Multiple Mechanisms of Photoreceptor Spectral Tuning in Heliconius Butterflies.Molecular biology and evolution · 2022Article
- Molecular Evolution of Ultraviolet Visual Opsins and Spectral Tuning of Photoreceptors in Anemonefishes (Amphiprioninae).Genome biology and evolution · 2021Article
- Behavioural red-light sensitivity in fish according to the optomotor response.Royal Society open science · 2021Article
- Axes of visual adaptation in the ecologically diverse family Cichlidae.Seminars in cell & developmental biology · 2020Review
- Tbx2a Modulates Switching of RH2 and LWS Opsin Gene Expression.Molecular biology and evolution · 2020Article
- Seeing the rainbow: mechanisms underlying spectral sensitivity in teleost fishes.The Journal of experimental biology · 2020Review
- Understanding the retinal basis of vision across species.Nature reviews. Neuroscience · 2020Review
- A detailed investigation of the visual system and visual ecology of the Barrier Reef anemonefish, Amphiprion akindynos.Scientific reports · 2019Article
- Diurnal variation in opsin expression and common housekeeping genes necessitates comprehensive normalization methods for quantitative real-time PCR analyses.Molecular ecology resources · 2019Article
- Color discrimination thresholds in a cichlid fish:The Journal of experimental biology · 2019Article
- Variable vision in variable environments: the visual system of an invasive cichlid (The Journal of experimental biology · 2019Article
- Parallel opsin switches in multiple cone types of the starry flounder retina: tuning visual pigment composition for a demersal life style.Scientific reports · 2018Article
- Novel Animal Model of Crumbs-Dependent Progressive Retinal Degeneration That Targets Specific Cone Subtypes.Investigative ophthalmology & visual science · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The distinct behaviours of animals and the varied habitats in which animals live place different requirements on their visual systems. A trade-off exists between resolution and sensitivity, with these properties varying across the retina. Spectral sensitivity, which affects both achromatic and chromatic (colour) vision, also varies across the retina, though the function of this inhomogeneity is less clear. We previously demonstrated spatially varying spectral sensitivity of double cones in the cichlid fish Metriaclima zebra owing to coexpression of different opsins. Here, we map the distributions of ganglion cells and cone cells and quantify opsin coexpression in single cones to show these also vary across the retina. We identify an area centralis with peak acuity and infrequent coexpression, which may be suited for tasks such as foraging and detecting male signals. The peripheral retina has reduced ganglion cell densities and increased opsin coexpression. Modeling of cichlid visual tasks indicates that coexpression might hinder colour discrimination of foraging targets and some fish colours. But, coexpression might improve contrast detection of dark objects against bright backgrounds, which might be useful for detecting predators or zooplankton. This suggests a trade-off between acuity and colour discrimination in the central retina versus lower resolution but more sensitive contrast detection in the peripheral retina. Significant variation in the pattern of coexpression among individuals, however, raises interesting questions about the selective forces at work.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.