Evidence map›Paper›PMID 27811066›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Transmembrane TNF-

Jinliang Li, Jharna R Das, Pingtao Tang, Zhe Han, Jyoti K Jaiswal, Patricio E Ray

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Childhood HIV-associated nephropathy: 36 years later.Pediatric nephrology (Berlin, Germany) · 2021
    Review
  11. Article
  12. Mechanisms of Proteinuria in HIV.Frontiers in medicine · 2021
    Review
  13. Article
  14. APOL1 polymorphisms and kidney disease: loss-of-function or gain-of-function?American journal of physiology. Renal physiology · 2019
    Review
  15. Review
  16. Review
  17. HIV-1 Infection of Renal Cells in HIV-Associated Nephropathy.Journal of the American Society of Nephrology : JASN · 2017
    Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jinliang LiCenters for *Genetic Medicine Research and.
Jharna R DasCenters for *Genetic Medicine Research and.
Pingtao TangCenters for *Genetic Medicine Research and.
Zhe HanDepartment of Pediatrics, and.
Jyoti K JaiswalCenters for *Genetic Medicine Research and.
Patricio E RayCenters for *Genetic Medicine Research and Pray@cnmc.org.
Pediatrics and Genetics · USChildren's National · US

Funding

Role of bFGF low affinity receptors in childhood HIVANR01DK049419 · NIDDK · UNIVERSITY OF VIRGINIA · PI PATRICIO E. RAY · 1994 to 2026
$7.4M
Role of heparin binding growth factors in vascular leakage and fatal bleedingR01HL102497 · NHLBI · UNIVERSITY OF VIRGINIA · PI RAY, PATRICIO E. · 2009 to 2018
$3.4M
Modeling Nephrotic Syndrome in Drosophila NephrocytesR01DK098410 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI HAN, ZHE · 2014 to 2022
$3.3M
Role of cytokines and APOL-1 in the pathogenesis of childhood HIV associated nephrologyR01DK103564 · NIDDK · UNIVERSITY OF VIRGINIA · PI RAY, PATRICIO E. · 2014 to 2023
$3.0M
Pathogenesis of chronic renal injury and hypertension in HIV-infected childrenR01DK108368 · NIDDK · UNIVERSITY OF VIRGINIA · PI RAY, PATRICIO E. · 2015 to 2019
$1.5M
NHLBI NIH HHS R01 HL102497NIDDK NIH HHS R01 DK049419NIDDK NIH HHS R01 DK098410NIDDK NIH HHS R01 DK103564NIDDK NIH HHS R01 DK108368
6 · The paper itself

Abstract

Studies have shown that podocytes and renal tubular epithelial cells from patients with HIV-associated nephropathy (HIVAN) express HIV-1 transcripts, suggesting that productive infection of renal epithelial cells precipitates development of HIVAN. However, podocytes and renal tubular epithelial cells do not express CD4 receptors, and it is unclear how these cells become productively infected

Indexed as

AIDS-Associated NephropathyCells, CulturedChildHIV-1HumansMembrane ProteinsPodocytesTumor Necrosis Factor-alphaMembrane ProteinsTumor Necrosis Factor-alphachildrencytokinesHIV nephropathypediatric nephrologypodocyterenal tubular epithelial cells

Identifiers

PMID27811066
PMCPMC5328167
OpenAlexW2548748939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.