Evidence map›Paper›PMID 27810993›Full record

ArticleHaematologica2017

Evaluation of bone marrow morphology is essential for assessing disease status in recombinant interferon α-treated polycythemia vera patients.

Elizabeth Margolskee, Spencer Krichevsky, Attilio Orazi, Richard T Silver

Registry-linked trialOpen access · goldAbstract readLetter
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04103645 (A 2-tiered, Phase 2, Rule-based, Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04103645 phase2terminatednot on this mapstarted 2019, after this paper: background citation

A 2-tiered, Phase 2, Rule-based, Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib (TEW-7197) in the Treatment of Anemic Patients With Philadelphia Chromosome-negative MPNs (Ph-neg MPNs)

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2019 to 2024Enrolled2ConditionsMyeloproliferative NeoplasmArmsVactosertib
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elizabeth MargolskeeDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Spencer KrichevskyRichard T. Silver Center for Myeloproliferative Neoplasms, Division of Hematology/Medical Oncology, Weill Cornell Medicine, New York, NY, USA.
Attilio OraziDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Richard T SilverRichard T. Silver Center for Myeloproliferative Neoplasms, Division of Hematology/Medical Oncology, Weill Cornell Medicine, New York, NY, USA rtsilver@med.cornell.edu.
Cornell University · USWeill Cornell Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationBiopsyBone MarrowDisease ManagementDrug MonitoringFemaleGene ExpressionHumansInterferon-alphaInterferon alpha-2Janus Kinase 2MaleMegakaryocytesMiddle AgedPolycythemia VeraPolyethylene GlycolsInterferon-alphaInterferon alpha-2JAK2 protein, humanJanus Kinase 2peginterferon alfa-2apeginterferon alfa-2bPolyethylene GlycolsRecombinant ProteinsSTAT5 Transcription Factor

Identifiers

PMID27810993
PMCPMC5394963
OpenAlexW2547042356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.