Evidence map›Paper›PMID 27810738›Full record

ArticleRedox biology2016

Hydroxytyrosol inhibits hydrogen peroxide-induced apoptotic signaling via labile iron chelation.

Natalia Kitsati, Michalis D Mantzaris, Dimitrios Galaris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. MAFLD: a ferroptotic disease.Trends in molecular medicine · 2026
    Review
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  17. Immunomodulatory and Antioxidant Drugs in Glaucoma Treatment.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Natalia KitsatiLaboratory of Biological Chemistry, University of Ioannina, School of Health Sciences, Faculty of Medicine, 451 10 Ioannina, Greece.
Michalis D MantzarisLaboratory of Biological Chemistry, University of Ioannina, School of Health Sciences, Faculty of Medicine, 451 10 Ioannina, Greece.
Dimitrios GalarisLaboratory of Biological Chemistry, University of Ioannina, School of Health Sciences, Faculty of Medicine, 451 10 Ioannina, Greece. Electronic address: dgalaris@uoi.gr.
University of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although it is known that Mediterranean diet plays an important role in maintaining human health, the underlying molecular mechanisms remain largely unknown. The aim of this investigation was to elucidate the potential role of ortho-dihydroxy group containing natural compounds in H

Indexed as

AntioxidantsApoptosisDNA DamageHumansHydrogen PeroxideIronJurkat CellsMAP Kinase Kinase 4Olive Oilp38 Mitogen-Activated Protein KinasesPhenylethyl AlcoholPhosphorylation3,4-dihydroxyphenylethanol4-hydroxyphenylethanolAntioxidantsHydrogen PeroxideIronMAP Kinase Kinase 4Olive Oilp38 Mitogen-Activated Protein KinasesPhenylethyl AlcoholApoptosisHydroxytyrosolLabile ironMitogen activated protein kinasesRedox signalingTyrosol

Identifiers

PMID27810738
PMCPMC5094689
OpenAlexW2535350081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.