ArticleEnvironmental research2017
The association of lead exposure during pregnancy and childhood anthropometry in the Mexican PROGRESS cohort.
Article in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03420872 (Prenatal and Childhood Nutrient Mixtures Predict Neurodevelopmental Outcomes Among Children in Mexico City), which is not on this map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prenatal and Childhood Nutrient Mixtures Predict Neurodevelopmental Outcomes Among Children in Mexico City
Who cites it
39 citing papers in PubMed.
- Association Between Lead Exposure and Anthropometric Indicators in School-aged Children: A Longitudinal Study.Biological trace element research · 2026Article
- Prenatal exposure to essential and toxic elements in relation to infant growth trajectories.Environmental health : a global access science source · 2026Article
- Identifying critical windows of susceptibility to perinatal lead exposure on child serum vaccine antibody levels.American journal of epidemiology · 2025Article
- Prenatal exposure to metal(loid)s mixture and childhood lung function: Exploring sex-specific associations.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Air pollution, temperature, and HbA1c levels among children in Mexico City, Mexico.Ecotoxicology and environmental safety · 2025Article
- Essential and non-essential metals in children's intellectual functioning: A multi-media biomarker approach from a Mexico City birth cohort.Environmental research · 2025Article
- The landscape of pregnancy and prepregnancy cohorts: a scoping review.BMC pregnancy and childbirth · 2025Article
- Prevalence of Exposure to Environmental Metal Mixtures Among Pregnant Women in the United States National Health and Nutrition Examination Survey (NHANES) 1999-2018.Journal of xenobiotics · 2025Article
- Associations of salivary aldosterone levels during pregnancy with maternal blood pressure and birth weight-for-gestational age in a Mexico City birth cohort.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Longitudinal associations between early-life fluoride exposures and cardiometabolic outcomes in school-aged children.Environment international · 2024Article
- Assessing lead exposure in U.S. pregnant women using biological and residential measurements.The Science of the total environment · 2023Article
- Quality and risk assessment of lead and cadmium in drinking water for child development centres use in Phatthalung province, Thailand.Environmental analysis, health and toxicology · 2023Article
- Article
- Biomarkers of maternal lead exposure during pregnancy using micro-spatial child deciduous dentine measurements.Environment international · 2022Article
- Article
- Prenatal lead exposure and childhood lung function: Influence of maternal cortisol and child sex.Environmental research · 2022Article
- Prenatal maternal phthalate exposures and trajectories of childhood adiposity from four to twelve years.Environmental research · 2022Article
- Lead exposure and serum metabolite profiles in pregnant women in Mexico City.Environmental health : a global access science source · 2021Article
- Prenatal blood lead levels and reduced preadolescent glomerular filtration rate: Modification by body mass index.Environment international · 2021Article
- Metal exposure and bone remodeling during pregnancy: Results from the PROGRESS cohort study.Environmental pollution (Barking, Essex : 1987) · 2021Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Lead exposure during pregnancy remains a public health problem with potential lifelong impacts on children's growth and development. Mexico is unique in that stunting and obesity are both major public health concerns in children. This situation might be exacerbated by lead exposure which remains more common in Mexico than in the United States due in part to the use of lead glazed pottery in food preparation and storage. Our objective is to determine how lead exposure during pregnancy is associated with children's growth parameters, including height, weight, body mass index and percentage body fat measured between ages 4-6 years old in a Mexico City pregnancy cohort. Blood lead was collected in the 2nd and 3rd trimester of pregnancy as well as at delivery. Bone lead was assessed in mothers as a long term exposure biomarker. We performed multivariable linear regression analyses to assess the association between each of these lead exposure biomarkers and child anthropometry. We found a significant negative association between maternal 3rd trimester blood lead concentration and offspring height for age (β-0.10; 95% CI -0.19, -0.01), and a negative association between maternal 3rd trimester blood lead concentration and weight for age (β-0.11; 95% CI -0.22,-0.003). Our results in this Mexican population add to previous findings of an association of lead and decreased stature and weight in early childhood. Ongoing follow-up and longitudinal analyses may help elucidate how this impacts growth trajectory and other children's health outcomes.
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