Evidence map›Paper›PMID 27810657›Full record

ArticleDrug and alcohol dependence2016

Interrelationships between marijuana demand and discounting of delayed rewards: Convergence in behavioral economic methods.

Elizabeth R Aston, Jane Metrik, Michael Amlung, Christopher W Kahler, James MacKillop

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A systematic review and meta-analysis of delay discounting and cannabis use.Experimental and clinical psychopharmacology · 2021
    Pooled it
  2. Pooled it
  3. Trial
  4. A web-based episodic specificity and future thinking session modulates delay discounting in cannabis users.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
    Trial
  5. Gimmie the Gummies: Initial validation of the Edibles Marijuana Purchase Task.Experimental and clinical psychopharmacology · 2026
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  14. Reliability of an adaptive marijuana purchase task.Experimental and clinical psychopharmacology · 2023
    Article
  15. Article
  16. Notes on demand: Conceptual and empirical benefits of applying Rachlin's discounting equation to demand data.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth R AstonCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI 02903, USA. Electronic address: Elizabeth_Aston@Brown.edu.
Jane MetrikCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI 02903, USA; Providence Veterans Affairs Medical Center, Providence, RI 02908, USA.
Michael AmlungPeter Boris Centre for Addictions Research, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, ON L8N 3K7, Canada.
Christopher W KahlerCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI 02903, USA.
James MacKillopCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI 02903, USA; Peter Boris Centre for Addictions Research, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, ON L8N 3K7, Canada; Homewood Research Institute, Guelph, ON N1E 6K9, Canada.

Funding

ALCOHOL INTERVENTION/TREATMENT OUTCOME RESEARCH TRAININGT32AA007459 · NIAAA · BROWN UNIVERSITY · PI ROBERT MIRANDA, PETER M. MONTI · 1986 to 2026
$13.3M
Behavioral Economic Analysis of Demand for MarijuanaK01DA039311 · NIDA · BROWN UNIVERSITY · PI ASTON, ELIZABETH · 2015 to 2019
$902k
Genetic variation and marijuana's pharmacologic and cue-elicted effectsR03DA027484 · NIDA · BROWN UNIVERSITY · PI KNOPIK, VALERIE S, METRIK, JANE · 2009 to 2010
$483k
NIAAA NIH HHS T32 AA007459NIDA NIH HHS K01 DA039311NIDA NIH HHS R03 DA027484
6 · The paper itself

Abstract

backgroundDistinct behavioral economic domains, including high perceived drug value (demand) and delay discounting (DD), have been implicated in the initiation of drug use and the progression to dependence. However, it is unclear whether frequent marijuana users conform to a "reinforcer pathology" addiction model wherein marijuana demand and DD jointly increase risk for problematic marijuana use and cannabis dependence (CD).

methodsParticipants (n=88, 34% female, 14% cannabis dependent) completed a marijuana purchase task at baseline. A delay discounting task was completed following placebo marijuana cigarette (0% THC) administration during a separate experimental session.

resultsMarijuana demand and DD were quantified using area under the curve (AUC). In multiple regression models, demand uniquely predicted frequency of marijuana use while DD did not. In contrast, DD uniquely predicted CD symptom count while demand did not. There were no significant interactions between demand and DD in either model.

conclusionsThese findings suggest that frequent marijuana users exhibit key constituents of the reinforcer pathology model: high marijuana demand and steep discounting of delayed rewards. However, demand and DD appear to be independent rather than synergistic risk factors for elevated marijuana use and risk for progression to CD. Findings also provide support for using AUC as a singular marijuana demand metric, particularly when also examining other behavioral economic constructs that apply similar statistical approaches, such as DD, to support analytic methodological convergence.

Indexed as

Delay DiscountingEconomics, BehavioralRewardAdolescentAdultBehavior, AddictiveCannabisCross-Sectional StudiesFemaleHumansMaleMarijuana AbuseMarijuana SmokingSurveys and QuestionnairesYoung AdultArea under the curveBehavioral economicsCannabis dependenceDelay discountingMarijuanaPurchase task

Identifiers

PMID27810657
PMCPMC5140845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.