Evidence map›Paper›PMID 27810637›Full record

ReviewCurrent opinion in genetics & development2016

Inferences of African evolutionary history from genomic data.

Marcia Holsbach Beltrame, Meagan A Rubel, Sarah A Tishkoff

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Multiethnic prevalence of theClinical kidney journal · 2025
    Article
  2. Review
  3. Review
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  7. Review
  8. Article
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  13. Marked variation in prevalence of malaria-protective human genetic polymorphisms across Uganda.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2017
    Article
  14. eLife · 2017
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcia Holsbach BeltrameDepartment of Genetics, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Meagan A RubelDepartment of Anthropology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sarah A TishkoffDepartment of Genetics, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: tishkoff@mail.med.upenn.edu.

Funding

PARASITOLOGY: MODERN APPROACHEST32AI007532 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 1998 to 2022
$5.0M
Integrative Genomics of Body Size and Metabolism in Ethnically Diverse AfricansR01GM113657 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI TISHKOFF, SARAH ANNE · 2015 to 2019
$2.8M
Integrative nutrigenomic and metabolomic analyses of Africans with variable dietsR01DK104339 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI TISHKOFF, SARAH ANNE · 2015 to 2018
$1.4M
NIAID NIH HHS T32 AI007532NIDDK NIH HHS R01 DK104339NIGMS NIH HHS R01 GM113657
6 · The paper itself

Abstract

Africa is the origin of anatomically modern humans and a continent of linguistic, cultural, environmental, phenotypic, and genetic diversity. However, African populations remain underrepresented in genetic studies, which have largely focused on individuals with European and Asian ancestry. The expansion of high-throughput 'omic' technologies to interrogate multiple tissue types across many biomolecules-DNA, proteins, epigenetic modifications, metabolites, and others-has heralded a new era of investigation into African history. In this review, we summarize how some of these recent advances have been applied to contemporary sub-Saharan African populations to inform studies on human origins and adaptation.

Indexed as

Evolution, MolecularGenetic VariationAfricaBlack PeopleGenetics, PopulationGenomicsHumansPhylogeny

Identifiers

PMID27810637
PMCPMC5161638

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.