ArticleJournal of pain and symptom management2017
Frequency and Predictors of Acute Hospitalization Before Death in Patients With Glioblastoma.
Article in Journal of pain and symptom management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Defining end-of-life in glioblastoma multiforme: a systematic review.Journal of neuro-oncology · 2025Pooled it
- Palliative care in glioblastoma patients: a systematic review.Revista da Associacao Medica Brasileira (1992) · 2024Pooled it
- Palliative care and end-of-life care in adults with malignant brain tumors.Neuro-oncology · 2023Pooled it
- Early palliative care decision in patients with primary brain tumor reduces emergency department visits and hospitalization at the end of life.Journal of neuro-oncology · 2025Article
- Disparities in end-of-life care and place of death in people with malignant brain tumors-A Swedish registry study.Neuro-oncology practice · 2025Article
- The impact of palliative care contact on the use of hospital resources at the end of life for brain tumor patients; a nationwide register-based cohort study.Journal of neuro-oncology · 2025Article
- Palliative Care in Neuro-oncology: an Update.Current neurology and neuroscience reports · 2023Review
- Palliative care referral across the disease trajectory in high-grade glioma.Journal of neuro-oncology · 2023Article
- Acute healthcare utilization in end-of-life among Swedish brain tumor patients - a population based register study.BMC palliative care · 2022Article
- Easing the Journey-an Updated Review of Palliative Care for the Patient with High-Grade Glioma.Current oncology reports · 2022Review
- Causes of Death and End-of-Life Care in Patients With Intracranial High-Grade Gliomas: A Retrospective Observational Study.Neurology · 2022Observational
- Aggressiveness of care at end of life in patients with high-grade glioma.Cancer medicine · 2021Article
- Ethics consultations in neuro-oncology.Neuro-oncology practice · 2021Article
- Palliative Care Service Utilization and Advance Care Planning for Adult Glioblastoma Patients: A Systematic Review.Cancers · 2021Review
- Palliative Care in High-Grade Glioma: A Review.Brain sciences · 2020Review
- Palliative Care in Patients With High-Grade Gliomas in the Neurological Intensive Care Unit.The Neurohospitalist · 2020Article
- Conceptualizing and Counting Discretionary Utilization in the Final 100 Days of Life: A Scoping Review.Journal of pain and symptom management · 2020Article
- Treatment of Glioblastoma in the Elderly.Drugs & aging · 2018Review
- Prognostic awareness and communication preferences among caregivers of patients with malignant glioma.Psycho-oncology · 2018Article
- Hospital-Based End-of-Life Care and Costs for Older Patients With Malignant Brain Tumors.JAMA oncology · 2017Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
contextGlioblastoma (GBM) is a devastating and incurable neuro-oncologic disease, and issues related to the end of life are almost invariably a matter of "when," not a matter of "if." Optimizing symptom management and quality of life in later stages of disease is of the utmost priority.
objectivesTo examine the frequency of and factors associated with late acute hospital admission before death in patients with GBM.
methodsCase-control study comparing patients with GBM admitted to the hospital within one month of death to those without late hospital admission.
resultsOf 385 GBM patients followed to death at Memorial Sloan Kettering Cancer Center, 164 (42.6%) were admitted within a month of death, most frequently (140, or 85%) to manage neurologic decline. Of these, 56 (34%) had intensive care unit care during this admission and 22 (13%), 18 (11%), and 2 (1%) received mechanical ventilation, enteral feeding tubes, or cardiopulmonary resuscitation, respectively. In multivariable analysis, in-hospital chaplaincy consultation, and participation in a therapeutic clinical trial, both at any time in the GBM disease course, were significantly associated with late hospital admission.
conclusionsLate hospitalization is frequent in GBM and often involves intensive care unit care in the management of clinical events that are part of the GBM dying process. Patients with a tendency to use religious support and those enrolled in clinical trials may be at greater risk for late hospitalization. Dedicated prospective study is needed to determine predictors of late hospitalization and to examine the impact of late acute medical care on quality of life in GBM.
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