Evidence map›Paper›PMID 27809884›Full record

ArticleBMC pulmonary medicine2016

Diffuse persistent pulmonary interstitial emphysema secondary to mechanical ventilation in bronchiolitis.

Blanca Toledo Del Castillo, Isabel Gordillo, Elena Rubio García, Sarah Nicole Fernández Lafever, Rafael Gonzalez Cortés, Javier Urbano Villaescusa, Jorge López González, María José Solana García, Jesús López-Herce Cid

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC pulmonary medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Blanca Toledo Del CastilloPediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Red de Investigación en Salud Materno-Infantil y del Desarrollo (Red SAMYD), C/ Doctor Castelo 47, 28009, Madrid, Spain. blankmajal@hotmail.com.
Isabel GordilloRadiology Department, Hospital General Universitario Gregorio Marañón, C/ Doctor Castelo 47, 28009, Madrid, Spain.
Elena Rubio GarcíaPediatric Department, Hospital General Universitario Gregorio Marañón, C/ Doctor Castelo 47, 28009, Madrid, Spain.
Sarah Nicole Fernández LafeverPediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Red de Investigación en Salud Materno-Infantil y del Desarrollo (Red SAMYD), C/ Doctor Castelo 47, 28009, Madrid, Spain.
Rafael Gonzalez CortésPediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Red de Investigación en Salud Materno-Infantil y del Desarrollo (Red SAMYD), C/ Doctor Castelo 47, 28009, Madrid, Spain.
Javier Urbano VillaescusaPediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Red de Investigación en Salud Materno-Infantil y del Desarrollo (Red SAMYD), C/ Doctor Castelo 47, 28009, Madrid, Spain.
Jorge López GonzálezPediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Red de Investigación en Salud Materno-Infantil y del Desarrollo (Red SAMYD), C/ Doctor Castelo 47, 28009, Madrid, Spain.
María José Solana GarcíaPediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Red de Investigación en Salud Materno-Infantil y del Desarrollo (Red SAMYD), C/ Doctor Castelo 47, 28009, Madrid, Spain.
Jesús López-Herce CidPediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Red de Investigación en Salud Materno-Infantil y del Desarrollo (Red SAMYD), C/ Doctor Castelo 47, 28009, Madrid, Spain.
Hospital General Universitario Gregorio Marañón · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersistent interstitial pulmonary emphysema (PIE) is a rare disease and it is even more uncommon in full-term infants, like our patient. When conservative management is not successful, surgical treatment should be considered. In our case, ECMO support was iniciated to keep the patient ventilated in order to allow the lung to heal using lung protection strategies. CASE PRESENTATION: We report an 18-day-old male infant with bronchiolitis that required mechanical ventilation with high positive airway pressures due to severe respiratory insufficiency. Chest X-rays and computed tomography scan revealed a severely hyperinflated left lung with extensive destructive changes and multiple small bullae. These findings were consistent with diffuse persistent interstitial emphysema (PIE), probably due to mechanical ventilation. The patient required high frequency oscillatory ventilation, inotropic support and continuous renal replacement therapy. He eventually suffered a cardiac arrest that required cardiopulmonary resuscitation and ECMO during 5 days with progressive clinical improvement and normalization of the X-ray.

conclusionWe present a patient with diffuse persistent interstitial emphysema who, despite an unfavorable evolution with different mechanical ventilation strategies, had a good response after ECMO assistance.

Indexed as

Extracorporeal Membrane OxygenationBronchiolitisHumansInfant, NewbornLungMalePulmonary EmphysemaRadiography, ThoracicRespiration, ArtificialRespiratory InsufficiencyTomography, X-Ray ComputedDiffuse persistent interstitial emphysemaECMOMechanical ventilationNeonatal

Identifiers

PMID27809884
PMCPMC5094036
OpenAlexW2548272211

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.