ArticleBMC complementary and alternative medicine2016
Anvillea garcinii extract inhibits the oxidative burst of primary human neutrophils.
Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Phagocytosis, Degranulation and Extracellular Traps Release by Neutrophils-The Current Knowledge, Pharmacological Modulation and Future Prospects.Frontiers in pharmacology · 2021Review
- Features of Neutrophils From Atopic and Non-Atopic Elite Endurance Runners.Frontiers in immunology · 2021Article
- Photodynamic therapy regulates fate of cancer stem cells through reactive oxygen species.World journal of stem cells · 2020Review
- In vitro pro-inflammatory enzyme inhibition and anti-oxidant potential of selected Sri Lankan medicinal plants.BMC complementary and alternative medicine · 2018Article
- Hepatoprotective and cytotoxic activities of Anvillea garcinii and isolation of four new secondary metabolites.Journal of natural medicines · 2018Article
- The role ofAvicenna journal of phytomedicineReview
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnvillea garcinii Coss. & Durieu (Anv) plant is used as a traditional North African medicine against several diseases associated with inflammation. At inflammatory sites, reactive oxygen species (ROS) produced in excess by activated phagocyte NADPH oxidase (NOX2) can accentuate inflammatory responses. Thus, we investigated if Anv-water soluble polysaccharides could modulate primary human neutrophil oxidative burst in vitro.
methodsHuman neutrophils were isolated from fresh whole blood and O
resultsWater soluble polysaccharides from Anv dose-dependently inhibited N-formyl-methionyl-leucyl-phenylalanine (fMLF)- and phorbol myristate acetate (PMA)-induced O
conclusionThe process of down-regulating NADPH oxidase by polysaccharides extracts from Anv provides new insights into the mechanism of Anv's anti-inflammatory actions.
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Registered trials
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