Evidence map›Paper›PMID 27809283›Full record

ArticleInternational journal of molecular sciences2016

Effect of High-Carbohydrate Diet on Plasma Metabolome in Mice with Mitochondrial Respiratory Chain Complex III Deficiency.

Jayasimman Rajendran, Nikica Tomašić, Heike Kotarsky, Eva Hansson, Vidya Velagapudi, Jukka Kallijärvi, Vineta Fellman

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jayasimman RajendranFolkhälsan Institute of Genetics, Folkhälsan Research Center, 00014 Helsinki, Finland. jayasimman.rajendran@helsinki.fi.
Nikica TomašićDepartment of Clinical Sciences, Lund, Pediatrics, Lund University, 22185 Lund, Sweden. nikica.tomasic@med.lu.se.
Heike KotarskyDepartment of Clinical Sciences, Lund, Pediatrics, Lund University, 22185 Lund, Sweden. heike.kotarsky@gmail.com.
Eva HanssonDepartment of Clinical Sciences, Lund, Pediatrics, Lund University, 22185 Lund, Sweden. eva.hansson@med.lu.se.
Vidya VelagapudiFinnish Institute of Molecular Medicine, University of Helsinki, 00290 Helsinki, Finland. vidya.velagapudi@helsinki.fi.
Jukka KallijärviFolkhälsan Institute of Genetics, Folkhälsan Research Center, 00014 Helsinki, Finland. jukka.kallijarvi@helsinki.fi.
Vineta FellmanFolkhälsan Institute of Genetics, Folkhälsan Research Center, 00014 Helsinki, Finland. vineta.fellman@med.lu.se.
University of Helsinki · FILund University · SEFolkhälsans Forskningscentrum · FIKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial disorders cause energy failure and metabolic derangements. Metabolome profiling in patients and animal models may identify affected metabolic pathways and reveal new biomarkers of disease progression. Using liver metabolomics we have shown a starvation-like condition in a knock-in (

Indexed as

Amino AcidsAnimalsATPases Associated with Diverse Cellular ActivitiesDietary CarbohydratesElectron Transport Complex IIILiver GlycogenMetabolomeMetabolomicsMice, Inbred C57BLMitochondrial DiseasesMitochondria, LiverMolecular ChaperonesMutationPrincipal Component AnalysisUreaAmino AcidsATPases Associated with Diverse Cellular ActivitiesBCS1L protein, mouseDietary CarbohydratesElectron Transport Complex IIILiver GlycogenMolecular ChaperonesUreaBCS1Ldextrose dietGRACILE syndromemetabolitemitochondrial disordermouse modelnutrition

Identifiers

PMID27809283
PMCPMC5133825
OpenAlexW2546958143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.