Evidence map›Paper›PMID 27809259›Full record

ArticleMolecules (Basel, Switzerland)2016

Anti-Inflammatory Potential of Ethyl Acetate Fraction of Moringa oleifera in Downregulating the NF-κB Signaling Pathway in Lipopolysaccharide-Stimulated Macrophages.

Palanisamy Arulselvan, Woan Sean Tan, Sivapragasam Gothai, Katyakyini Muniandy, Sharida Fakurazi, Norhaizan Mohd Esa, Abdullah A Alarfaj, S Suresh Kumar

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Potential ofNutrients · 2020
    Pooled it
  2. Effects ofNutrients · 2022
    Trial
  3. Glucosinolate Derivatives: Emerging Anti-Inflammatory Agents.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Exploring the Therapeutic Benefits ofCurrent drug research reviews · 2026
    Review
  6. HarnessingInternational journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Anti-Inflammatory Potential of 3-Hydroxy-β-Ionone fromMolecules (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Frontiers in pharmacology · 2024
    Review
  13. Incorporation ofMolecules (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Article
  16. Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  17. The Potential ofCells · 2022
    Review
  18. Article
  19. Review
  20. Evaluation of Anti-Inflammatory Effect ofPlants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Palanisamy ArulselvanLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. arulbio@gmail.com.
Woan Sean TanLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. wansen.0801@gmail.com.
Sivapragasam GothaiLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. gothai_86@yahoo.com.
Katyakyini MuniandyLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. katyakyini_2708@hotmail.com.
Sharida FakuraziLaboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. sharida.fakurazi@gmail.com.
Norhaizan Mohd EsaDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. nhaizan@upm.edu.my.
Abdullah A AlarfajDepartment of Botany and Microbiology, King Saud University, Riyadh 11451, Saudi Arabia. aalarfajj@ksu.edu.sa.
S Suresh KumarDepartment of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia. sureshkudsc@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present investigation, we prepared four different solvent fractions (chloroform, hexane, butanol, and ethyl acetate) of

Indexed as

Plant ExtractsAcetatesAnimalsDown-RegulationLipopolysaccharidesMiceMoringa oleiferaNF-kappa BRAW 264.7 CellsSignal TransductionAcetatesethyl acetateLipopolysaccharidesNF-kappa BPlant Extractsinflammationinflammatory mediatorsIκBαproinflammatory cytokinesRAW264.7 cells

Identifiers

PMID27809259
PMCPMC6273666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.