Evidence map›Paper›PMID 27808453›Full record

ArticleJournal of viral hepatitis2017

Phylogenetic analysis of full-length, early infection, hepatitis C virus genomes among people with intravenous drug use: the InC

C Rodrigo, A A Eltahla, R A Bull, F Luciani, J Grebely, G J Dore, T Applegate, K Page, J Bruneau, M D Morris and 11 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of viral hepatitis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  5. Genomic characterization of hepatitis C virus transmitted founder variants with deep sequencing.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 4 countries.

C RodrigoSchool of Medical Sciences, UNSW, Sydney, NSW, Australia.
A A EltahlaSchool of Medical Sciences, UNSW, Sydney, NSW, Australia.
R A BullSchool of Medical Sciences, UNSW, Sydney, NSW, Australia.
F LucianiSchool of Medical Sciences, UNSW, Sydney, NSW, Australia.
J GrebelyThe Kirby Institute, UNSW, Sydney, NSW, Australia.
G J DoreThe Kirby Institute, UNSW, Sydney, NSW, Australia.
T ApplegateThe Kirby Institute, UNSW, Sydney, NSW, Australia.
K PageUniversity of New Mexico, Albuquerque, NM, USA.
J BruneauCRCHUM, Université de Montréal, Montreal, QC, Canada.
M D MorrisUniversity of California, San Francisco, CA, USA.
A L CoxJohns Hopkins Medical Institutions, Baltimore, MD, USA.
W OsburnJohns Hopkins Medical Institutions, Baltimore, MD, USA.
A Y KimHarvard Medical School, Boston, MA, USA.
N H ShoukryCRCHUM, Université de Montréal, Montreal, QC, Canada.
G M LauerHarvard Medical School, Boston, MA, USA.
L MaherThe Kirby Institute, UNSW, Sydney, NSW, Australia.
J SchinkelAcademic Medical Center, Amsterdam, The Netherlands.
M PrinsAcademic Medical Center, Amsterdam, The Netherlands.
M HellardBurnet Institute, Melbourne, Vic, Australia.
A R LloydSchool of Medical Sciences, UNSW, Sydney, NSW, Australia.
InC3 Collaborative
UNSW Sydney · AUHarvard University · USJohns Hopkins University · USUniversité de Montréal · CAAcademic Medical Center · NLBurnet Institute · AUGGD Amsterdam · NLUniversity of California, San Francisco · USUniversity of New Mexico · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Acute Hepatitis C Infection in Young InjectorsR01DA016017 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PAGE, KIMBERLY · 2002 to 2018
$14.0M
The role of NK cells during acute HCV infection and antiviral therapyU19AI066345 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI KIM, ARTHUR Y · 2005 to 2014
$8.5M
Scientific CoreU19AI088791 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SHAW, GEORGE M · 2010 to 2020
$8.2M
Treatment of recently acquired hepatitis C virus infectionR01DA015999 · NIDA · UNIVERSITY OF NEW SOUTH WALES · PI DORE, GREGORY JOHN · 2003 to 2014
$3.7M
International Collaborative of prospective studies of HIV and Hepatitis in IDUR01DA031056 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PAGE, KIMBERLY · 2011 to 2015
$2.2M
Understanding the interpersonal context of HIV/HCV risk within injecting dyadsK01DA037802 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MORRIS, MEGHAN D · 2014 to 2018
$913k
CIHR MOP-103138CIHR MOP-106468NIAID NIH HHS P30 AI094189NIAID NIH HHS U19 AI066345NIAID NIH HHS U19 AI088791NIDA NIH HHS K01 DA037802NIDA NIH HHS R01 DA015999NIDA NIH HHS R01 DA016017NIDA NIH HHS R01 DA031056
6 · The paper itself

Abstract

Cross-continental phylogenetic analysis is important to understand subtle molecular differences of currently circulating hepatitis C virus (HCV) subtypes. Existence of such differences can be crucial in pursuing a universal hepatitis C vaccine. We characterized molecular epidemiology of early HCV infections identified across nine cohorts [North America (n=4), Australia (n=4) and Europe (n=1)] in the International Collaborative of Incident HIV and Hepatitis C in Injecting Cohorts (InC

Indexed as

PhylogenyAdultAustraliaDrug UsersEuropeFemaleGenome, ViralGenotypeHepacivirusHepatitis CHigh-Throughput Nucleotide SequencingHumansMaleMolecular EpidemiologyNorth AmericaPlasmaHepatitis C virusmolecular epidemiologyNGSpeople who inject drugsphylogenetics

Identifiers

PMID27808453
PMCPMC5191976
OpenAlexW2547009557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.