Evidence map›Paper›PMID 27808114›Full record

ArticleScientific reports2016

Cassava brown streak virus has a rapidly evolving genome: implications for virus speciation, variability, diagnosis and host resistance.

Titus Alicai, Joseph Ndunguru, Peter Sseruwagi, Fred Tairo, Geoffrey Okao-Okuja, Resty Nanvubya, Lilliane Kiiza, Laura Kubatko, Monica A Kehoe, Laura M Boykin

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
26.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 88 citations in OpenAlex.

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  12. Genetic diversity of whitefly (Journal of pest science · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Titus AlicaiNational Crops Resources Research Institute, P.O. Box 7084, Kampala, Uganda.
Joseph NdunguruMikocheni Agricultural Research Institute, Coca cola Road, Box 6226, Dar es Salaam, Tanzania.
Peter SseruwagiMikocheni Agricultural Research Institute, Coca cola Road, Box 6226, Dar es Salaam, Tanzania.
Fred TairoMikocheni Agricultural Research Institute, Coca cola Road, Box 6226, Dar es Salaam, Tanzania.
Geoffrey Okao-OkujaNational Crops Resources Research Institute, P.O. Box 7084, Kampala, Uganda.
Resty NanvubyaNational Crops Resources Research Institute, P.O. Box 7084, Kampala, Uganda.
Lilliane KiizaNational Crops Resources Research Institute, P.O. Box 7084, Kampala, Uganda.
Laura KubatkoThe Ohio State University, 154W 12th Avenue, Columbus, Ohio 43210, USA.
Monica A KehoeCrop Protection Branch, Department of Agriculture and Food, Western Australia, Bentley Delivery Centre, Perth, 6983, Western Australia, Australia.
Laura M BoykinThe University of Western Australia, ARC Centre of Excellence in Plant Energy Biology and School of Chemistry and Biochemistry, Crawley, Perth 6009, Western Australia, Australia.
National Agricultural Research Institute · UGMikocheni Agricultural Research Institute · TZAgriculture and Food · AUThe Ohio State University · USUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cassava is a major staple food for about 800 million people in the tropics and sub-tropical regions of the world. Production of cassava is significantly hampered by cassava brown streak disease (CBSD), caused by Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). The disease is suppressing cassava yields in eastern Africa at an alarming rate. Previous studies have documented that CBSV is more devastating than UCBSV because it more readily infects both susceptible and tolerant cassava cultivars, resulting in greater yield losses. Using whole genome sequences from NGS data, we produced the first coalescent-based species tree estimate for CBSV and UCBSV. This species framework led to the finding that CBSV has a faster rate of evolution when compared with UCBSV. Furthermore, we have discovered that in CBSV, nonsynonymous substitutions are more predominant than synonymous substitution and occur across the entire genome. All comparative analyses between CBSV and UCBSV presented here suggest that CBSV may be outsmarting the cassava immune system, thus making it more devastating and harder to control.

Indexed as

Evolution, MolecularGenetic SpeciationGenome, ViralAmino AcidsBase SequenceDisease ResistanceGenetic VariationHigh-Throughput Nucleotide SequencingManihotPhylogenyPlant DiseasesPlant LeavesPlant StemsPotyviridaeSelection, GeneticUgandaAmino Acids

Identifiers

PMID27808114
PMCPMC5093738
OpenAlexW2553834531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.