Evidence map›Paper›PMID 27808106›Full record

ArticleScientific reports2016

C2-domain mediated nano-cluster formation increases calcium signaling efficiency.

Mike Bonny, Xin Hui, Julia Schweizer, Lars Kaestner, André Zeug, Karsten Kruse, Peter Lipp

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The Min-protein oscillations inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Review
  6. Article
  7. Tetraspanins Function as Regulators of Cellular Signaling.Frontiers in cell and developmental biology · 2017
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mike BonnyTheoretical Physics, Saarland University, Saarbrücken, Germany.
Xin HuiInstitute for Molecular Cell Biology, Medical Faculty, Saarland University, Homburg/Saar, Germany.
Julia SchweizerInstitute for Molecular Cell Biology, Medical Faculty, Saarland University, Homburg/Saar, Germany.
Lars KaestnerInstitute for Molecular Cell Biology, Medical Faculty, Saarland University, Homburg/Saar, Germany.
André ZeugCellular Neurophysiology, Center of Physiology, Hannover Medical School, Hannover, Germany.
Karsten KruseTheoretical Physics, Saarland University, Saarbrücken, Germany.
Peter LippInstitute for Molecular Cell Biology, Medical Faculty, Saarland University, Homburg/Saar, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional protein kinase Cs (cPKCs) are key signaling proteins for transducing intracellular Ca

Indexed as

Calcium SignalingCalciumCell MembraneComputer SimulationFluorescence Resonance Energy TransferHEK293 CellsHumansMacromolecular SubstancesNanoparticlesProtein DomainsProtein Kinase C-alphaStochastic ProcessesStructure-Activity RelationshipTetradecanoylphorbol AcetateCalciumMacromolecular SubstancesProtein Kinase C-alphaTetradecanoylphorbol Acetate

Identifiers

PMID27808106
PMCPMC5093555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.