Evidence map›Paper›PMID 27807651›Full record

ArticleLasers in medical science2017

Comparison of the alendronate and irradiation with a light-emitting diode (LED) on murine osteoclastogenesis.

Hong Moon Sohn, Youngjong Ko, Mineon Park, Bora Kim, Jung Eun Park, Donghwi Kim, Young Lae Moon, Wonbong Lim

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Effects of Photobiomodulation on MC3T3-E1 Cells via 630 nm and 810 nm Light-Emitting Diode.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hong Moon SohnDepartment of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju, Korea.
Youngjong KoDepartment of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju, Korea.
Mineon ParkDepartment of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju, Korea.
Bora KimDepartment of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju, Korea.
Jung Eun ParkDepartment of Biomedical Science, BK21-Plus Research Team for Bioactive Control, Chosun University, Gwangju, Korea.
Donghwi KimDepartment of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju, Korea.
Young Lae MoonDepartment of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju, Korea.
Wonbong LimDepartment of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju, Korea. wonbong@chosun.ac.kr.
Chosun University Hospital · KRChosun University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photomodulation therapy (PBMT) using light-emitting diode (LED) has been proposed as an alternative to conventional osteoporosis therapies. Our aim was to determine the effect of irradiation with a light-emitting diode on receptor activator of NF-κB ligand (RANKL)-mediated differentiation of mouse bone marrow macrophages into osteoclasts and compare it to alendronate treatment. The cells were irradiated with LED at 635±10 nm, 9-cm spot size, 5 mW/cm

Indexed as

LightAlendronateAnimalsBone Marrow CellsBone ResorptionCell DifferentiationDown-RegulationExtracellular Signal-Regulated MAP KinasesMacrophagesMaleMice, Inbred BALB CNF-kappa BOsteoclastsOsteogenesisPhosphorylationRANK LigandAlendronateExtracellular Signal-Regulated MAP KinasesNF-kappa BRANK LigandReactive Oxygen SpeciesReceptor Activator of Nuclear Factor-kappa BRNA, MessengerLEDOsteoclastogenesisOsteoporosisROS

Identifiers

PMID27807651
OpenAlexW2547791514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.