SynthesisArchives of gynecology and obstetrics2017
Maternal lipid profile and the relation with spontaneous preterm delivery: a systematic review.
Synthesis in Archives of gynecology and obstetrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- The establishment of lipid profiles reference ranges during pregnancy: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2025Pooled it
- Maternal metabolic factors and the association with gestational diabetes: A systematic review and meta-analysis.Diabetes/metabolism research and reviews · 2022Pooled it
- The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: a systematic review.BMC infectious diseases · 2017Pooled it
- Maternal Serum Lipid Trajectories and Association with Pregnancy Loss and Length of Gestation.American journal of perinatology · 2020Trial
- First-trimester inflammation and dyslipidemia in preterm delivery: the role of monocyte-to-HDL cholesterol ratio and lipid profiles.Irish journal of medical science · 2025Article
- Article
- The association between pregnancy levels of blood lipids and the risk of preterm birth.Scientific reports · 2024Article
- Intrapartum Factors Affecting Abnormal Lipid Profiles in Early Postpartum Period.Journal of personalized medicine · 2023Article
- Preconception Cardiometabolic Markers and Birth Outcomes Among Women in the Hispanic Community Health Study/Study of Latinos.Journal of women's health (2002) · 2022Article
- Associations of maternal lipoprotein particle distribution in mid-pregnancy with birth outcomes: a pilot study.Lipids in health and disease · 2022Article
- Biomarkers of pre-pregnancy allostatic load and subsequent adverse birth outcomes.SSM - population health · 2022Article
- Lipid and lipoprotein concentrations during pregnancy and associations with ethnicity.BMC pregnancy and childbirth · 2022Article
- A Novel Review of Homocysteine and Pregnancy Complications.BioMed research international · 2021Review
- Cardiovascular Disease-Related Pregnancy Complications Are Associated with Increased Maternal Levels and Trajectories of Cardiovascular Disease Biomarkers During and After Pregnancy.Journal of women's health (2002) · 2020Article
- Lipidome Profiles Are Related to Depressive Symptoms and Preterm Birth Among African American Women.Biological research for nursing · 2020Article
- Black Box Warning: Cardiovascular Complications Make Motherhood Unsafe for African American Women.World journal of gynecology & womens health · 2020Article
- Metabolic syndrome in pregnancy and risk for adverse pregnancy outcomes: A prospective cohort of nulliparous women.PLoS medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is unknown whether an unfavorable (atherogenic) lipid profile and homocysteine level, which could supersede clinical cardiovascular disease, is also associated with an increased risk of spontaneous preterm delivery (sPTD). A systematic review of studies assessing the lipid profile and homocysteine value of women with sPTD compared to women with term delivery in pre-pregnancy and during pregnancy.
methodsA systematic search of peer-reviewed articles published between January 1980 and May 2014 was performed using MEDLINE, EMBASE and the Cochrane database. We included case-control and cohort studies that examined triglycerides, high/low density lipoprotein cholesterol, total cholesterol and homocysteine in women with sPTD. Articles were subdivided in pre-pregnancy, first, second and third trimester. Of 708 articles reviewed for eligibility, 14 met our inclusion criteria. RESULTS AND
conclusionNine cohort studies and five case-control studies were analyzed, reporting on 1466 cases with sPTD and 11296 controls with term delivery. The studies suggest a possible elevated risk of sPTD in woman with high TG levels, no association of high and low density lipoprotein cholesterol with the risk of sPTD was found. High homocysteine levels are associated with sPTD in the second trimester. The role of triglycerides and homocysteine in sPTD should be explored further.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.