Evidence map›Paper›PMID 27807517›Full record

ArticleJournal of exercise rehabilitation2016

Delayed voluntary exercise does not enhance cognitive performance after hippocampal injury: an investigation of differentially distributed exercise protocols.

Elise Wogensen, Marie Gajhede Gram, Jens Bak Sommer, Christina Rytter Vilsen, Jesper Mogensen, Hana Malá

Abstract read
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In one paragraph

Article in Journal of exercise rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elise WogensenThe Unit for Cognitive Neuroscience, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
Marie Gajhede GramThe Unit for Cognitive Neuroscience, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
Jens Bak SommerDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Christina Rytter VilsenThe Unit for Cognitive Neuroscience, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
Jesper MogensenThe Unit for Cognitive Neuroscience, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
Hana MaláThe Unit for Cognitive Neuroscience, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Voluntary exercise has previously been shown to enhance cognitive recovery after acquired brain injury (ABI). The present study evaluated effects of two differentially distributed protocols of delayed, voluntary exercise on cognitive recovery using an allocentric place learning task in an 8-arm radial maze. Fifty-four Wistar rats were subjected to either bilateral transection of the fimbria-fornix (FF) or to sham surgery. Twenty-one days postinjury, the animals started exercising in running wheels either for 14 consecutive days (FF/exercise daily [ExD], sham/ExD) or every other day for 14 days (FF/exercise every second day [ExS], sham/ExS). Additional groups were given no exercise treatment (FF/not exercise [NE], sham/NE). Regardless of how exercise was distributed, we found no cognitively enhancing effects of exercise in the brain injured animals. Design and protocol factors possibly affecting the efficacy of post-ABI exercise are discussed.

Indexed as

Animal modelBrain injuryCognitive recoveryHippocampusSpatial learningVoluntary exercise

Identifiers

PMID27807517
PMCPMC5091054

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.