Evidence map›Paper›PMID 27807498›Full record

ArticleCancer biology & medicine2016

Advances in biodegradable nanomaterials for photothermal therapy of cancer.

Chao-Feng He, Shun-Hao Wang, Ying-Jie Yu, He-Yun Shen, Yan Zhao, Hui-Ling Gao, Hai Wang, Lin-Lin Li, Hui-Yu Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer biology & medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Self-assembled injectable Icariin@ TiJournal of materials science. Materials in medicine · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
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  11. Article
  12. Polydopamine-Functionalized CA-(PCL-Frontiers in pharmacology · 2018
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chao-Feng HeSchool of Material Science and Engineering, Henan Polytechnic University, Jiaozuo 454000, China; Beijing Key Laboratory of Bioprocess, Beijing University of Chemical Technology, Beijing 100029, China.
Shun-Hao WangBeijing Key Laboratory of Bioprocess, Beijing University of Chemical Technology, Beijing 100029, China.
Ying-Jie YuDepartment of Materials Science and Engineering, State University of New York at Stony Brook, Stony Brook, NY 11790, USA.
He-Yun ShenBeijing Key Laboratory of Bioprocess, Beijing University of Chemical Technology, Beijing 100029, China.
Yan ZhaoDepartment of Emergency, Shandong Heze Municipal Hospital, Heze 274031, China.
Hui-Ling GaoBeijing Key Laboratory of Bioprocess, Beijing University of Chemical Technology, Beijing 100029, China.
Hai WangCAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China.
Lin-Lin LiBeijing Institute of Nanoenergy and Nanosystems, National Center for Nanoscience and Technology (NCNST), Chinese Academy of Sciences, Beijing 100083, China.
Hui-Yu LiuBeijing Key Laboratory of Bioprocess, Beijing University of Chemical Technology, Beijing 100029, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photothermal cancer therapy is an alternative to chemotherapy, radiotherapy, and surgery. With the development of nanophotothermal agents, this therapy holds immense potential in clinical translation. However, the toxicity issues derived from the fact that nanomaterials are trapped and retained in the reticuloendothelial systems limit their biomedical application. Developing biodegradable photothermal agents is the most practical route to address these concerns. In addition to the physicochemical properties of nanomaterials, various internal and external stimuli play key roles on nanomaterials uptake, transport, and clearance. In this review, we summarized novel nanoplatforms for photothermal therapy; these nanoplatforms can elicit stimuli-triggered degradation. We focused on the recent innovative designs endowed with biodegradable photothermal agents under different stimuli, including enzyme, pH, and near-infrared (NIR) laser.

Indexed as

biodegradabilityenzyme stimulinear-infrared laser stimuliPhotothermal therapypH stimuli

Identifiers

PMID27807498
PMCPMC5069834

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.