ArticleArchives of disease in childhood. Fetal and neonatal edition2017
Influence of own mother's milk on bronchopulmonary dysplasia and costs.
Article in Archives of disease in childhood. Fetal and neonatal edition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Economic evaluations of human milk for very preterm infants: a systematic review.Frontiers in pediatrics · 2025Pooled it
- Pooled it
- Mother's Own Milk and Bronchopulmonary Dysplasia: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2019Pooled it
- A Systematic Review and Meta-Analysis of Human Milk Feeding and Morbidity in Very Low Birth Weight Infants.Nutrients · 2018Pooled it
- Lung Recruitment Before Surfactant Administration in Extremely Preterm Neonates: 2-Year Follow-Up of a Randomized Clinical Trial.JAMA network open · 2024Trial
- IQ Was Not Improved by Post-Discharge Fortification of Breastmilk in Very Preterm Infants.Nutrients · 2022Trial
- Impact of post-NICU human milk intake on respiratory outcomes in bronchopulmonary dysplasia.Pediatric research · 2026Article
- Review
- A quality improvement intervention to improve medium-term breastfeeding in moderate- and late-preterm infants.International breastfeeding journal · 2025Article
- Type and Volume of Milk Intake in Premature Infants <33 Weeks Gestational Age in the Neonatal Intensive Care Unit.Children (Basel, Switzerland) · 2025Article
- Mother's Own Milk Provision During the First 12 Weeks of Life by Gestational Age.JAMA network open · 2025Article
- Human milk and bronchopulmonary dysplasia have a dose-dependent effect: a cohort study.BMJ paediatrics open · 2025Article
- Article
- Interventions to improve racial and ethnic equity in critical care: A scoping review.PloS one · 2025Article
- Mother's own milk and bronchopulmonary dysplasia in appropriate for gestational age preterm infants.European journal of clinical nutrition · 2024Article
- Multi-prong quality improvement approach for increasing mother's own milk use for very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Observational
- Monitoring the Use of Human Milk, the Ideal Food for Very Low-Birth-Weight Infants-A Narrative Review.Foods (Basel, Switzerland) · 2024Review
- The association of different types of human milk with bronchopulmonary dysplasia in preterm infants.Frontiers in nutrition · 2024Article
- Research progress on pathophysiologic mechanisms, clinical treatment and predictive biomarkers in bronchopulmonary dysplasia: from the perspective of oxidative stress.Frontiers in pediatrics · 2024Review
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Authors and funding
11 authors.
Funding
Abstract
backgroundHuman milk from the infant's mother (own mother's milk; OMM) feedings reduces the risk of several morbidities in very low birthweight (VLBW) infants, but limited data exist regarding its impact on bronchopulmonary dysplasia (BPD).
objectiveTo prospectively study the impact of OMM received in the neonatal intensive care unit (NICU) on the risk of BPD and associated costs. DESIGN/
methodsA 5-year prospective cohort study of the impact of OMM dose on growth, morbidity and NICU costs in VLBW infants. OMM dose was the proportion of enteral intake that consisted of OMM from birth to 36 weeks postmenstrual age (PMA) or discharge, whichever occurred first. BPD was defined as the receipt of oxygen and/or positive pressure ventilation at 36 weeks PMA. NICU costs included hospital and physician costs.
resultsThe cohort consisted of 254 VLBW infants with mean birth weight 1027±257 g and gestational age 27.8±2.5 weeks. Multivariable logistic regression demonstrated a 9.5% reduction in the odds of BPD for every 10% increase in OMM dose (OR 0.905 (0.824 to 0.995)). After controlling for demographic and clinical factors, BPD was associated with an increase of US$41 929 in NICU costs.
conclusionsIncreased dose of OMM feedings from birth to 36 weeks PMA was associated with a reduction in the odds of BPD in VLBW infants. Thus, high-dose OMM feeding may be an inexpensive, effective strategy to help reduce the risk of this costly multifactorial morbidity.
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