Evidence map›Paper›PMID 27806940›Full record

ArticleAmerican journal of physiology. Cell physiology2017

NADPH oxidase-2 mediates zinc deficiency-induced oxidative stress and kidney damage.

Mirandy S Li, Sherry E Adesina, Carla L Ellis, Jennifer L Gooch, Robert S Hoover, Clintoria R Williams

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. SLC39A8-mediated zinc dyshomeostasis potentiates kidney disease.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mirandy S LiSchool of Medicine, Emory University, Atlanta, Georgia.
Sherry E AdesinaSchool of Medicine, Emory University, Atlanta, Georgia.
Carla L EllisSchool of Medicine, Emory University, Atlanta, Georgia.
Jennifer L GoochSchool of Medicine, Emory University, Atlanta, Georgia.
Robert S HooverSchool of Medicine, Emory University, Atlanta, Georgia.
Clintoria R WilliamsSchool of Medicine, Emory University, Atlanta, Georgia; clricha@emory.edu.
Emory University · USPhiladelphia College of Osteopathic Medicine · US

Funding

Nephrology Institutional Training Grant FLSA SupplementT32DK007656 · NIDDK · EMORY UNIVERSITY · PI SANDS, JEFF M, WALL, SUSAN MARIE · 1990 to 2020
$3.5M
Summer Undergraduate Program in Emory Renal Research (SUPERR)R25DK101390 · NIDDK · EMORY UNIVERSITY · PI Jason Cobb, Jeanie Park · 2014 to 2026
$1.4M
NIDDK NIH HHS R25 DK101390NIDDK NIH HHS T32 DK007656
6 · The paper itself

Abstract

Zn

Indexed as

Oxidative StressAnimalsFemaleKidneyMaleMiceNADPH OxidasesRenal Insufficiency, ChronicZincNADPH OxidasesNox3 protein, mouseZinckidneyNADPH oxidaseoxidative stressreactive oxygen specieszinc deficiency

Identifiers

PMID27806940
PMCPMC5283897
OpenAlexW2547766238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.