Evidence map›Paper›PMID 27806861›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2016

Childhood Factors Affecting Persistence and Desistence of Attention-Deficit/Hyperactivity Disorder Symptoms in Adulthood: Results From the MTA.

Arunima Roy, Lily Hechtman, L Eugene Arnold, Margaret H Sibley, Brooke S G Molina, James M Swanson, Andrea L Howard, MTA Cooperative Group

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Arunima RoyDivision of Child Psychiatry, McGill University, Montreal Children's Hospital, Montreal, Quebec, Canada; Interdisciplinary Centre Psychopathology and Emotion Regulation, University of Groningen, University Medical Centre Groningen, The Netherlands.
Lily HechtmanDivision of Child Psychiatry, McGill University, Montreal Children's Hospital, Montreal, Quebec, Canada. Electronic address: lily.hechtman@mcgill.ca.
L Eugene ArnoldOhio State University, Nisonger Center, Columbus.
Margaret H SibleyFlorida International University, Miami.
Brooke S G MolinaUniversity of Pittsburgh School of Medicine.
James M SwansonChild Development Center, School of Medicine, University of California, Irvine.
Andrea L HowardCarleton University, Ottawa, Ontario.
MTA Cooperative Group
Montreal Children's Hospital · CAThe Ohio State University Wexner Medical Center · USUniversity of California, Irvine · USUniversity of Pittsburgh · USCarleton University · CAFlorida International University · USUniversity Medical Center Groningen · NL

Funding

Pathways to adult substance use and abuse from childhood ADHD in the MTAR01DA039881 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2015 to 2018
$1.1M
MULTISITE MULTIMODALITY TREATMENT STUDY OF ADHD/ADDU01MH050440 · NIMH · UNIVERSITY OF CALIFORNIA IRVINE · PI SWANSON, JAMES M · 1992 to 2000
$17k
MULTISITE MULTIMODAL TREATMENT STUDY OF ADHD/ADDU01MH050453 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ABIKOFF, HOWARD B · 1992 to 2000
$17k
PHARMACOLOGIC AND PSYCHOSOCIAL INTERVENTIONS FOR ADHDU01MH050461 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HINSHAW, STEPHEN P · 1992 to 2000
$17k
PHARMACOLOGICAL AND PSYCHOSOCIAL TREATMENT FOR ADHDU01MH050467 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PELHAM, WILLIAM E · 1992 to 2000
$17k
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION-278012011N01MH012011 · NIMH · UNIVERSITY OF CALIFORNIA, IRVI · PI SWANSON, JAMES · 2002 to 2006
–
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION-278012004N01MH012004 · NIMH · NEW YORK UNIVERSITY SCHOOL OF · PI ABIKOFF, HOWARD BARRY · 2002 to 2006
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FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION-278012012N01MH012012 · NIMH · DUKE UNIVERSITY MEDICAL CENTER · 2002 to 2004
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FOLLOW UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION-278012007N01MH012007 · NIMH · RES. FOUND. FOR MENTAL HEALTH, · PI GREENHILL, LARRY LEE · 2002 to 2006
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FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION-278012008N01MH012008 · NIMH · MCGILL UNIVERSITY · PI HECHTMAN, LILY T. · 2002 to 2006
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FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION-278012009N01MH012009 · NIMH · UNIVERSITY OF CALIFORNIA, BERK · PI HINSHAW, STEPHEN · 2002 to 2006
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FOLLOW UP OF THE MULTIMODAL TREATMETN STUDY OF CHILDREN WITH ATTENTION-278012010N01MH012010 · NIMH · UNIVERSITY OF PITTSBURGH · PI SG MOLINA, BROOKE · 2002 to 2006
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6 · The paper itself

Abstract

objectiveTo determine childhood factors that predict attention-deficit/hyperactivity disorder (ADHD) persistence and desistence in adulthood.

methodRegression analyses were used to determine associations between childhood factors and adult ADHD symptom persistence in 453 participants (mean age, 25 years) from the Multimodal Treatment Study of Children with ADHD (MTA). Childhood IQ, total number of comorbidities, child-perceived parenting practices, child-perceived parent-child relationships, parental mental health problems, marital problems of parents, household income levels, and parental education were assessed at a mean age of 8 years in all participants. Adult ADHD persistence was defined using DSM-5 symptom counts either with or without impairment, as well as mean ADHD symptom scores on the Conners' Adult ADHD Rating Scale (CAARS). Age, sex, MTA site, and childhood ADHD symptoms were covaried.

resultsThe most important childhood predictors of adult ADHD symptom persistence were initial ADHD symptom severity (odds ratio [OR] = 1.89, standard error [SE] = 0.28, p = .025), comorbidities (OR = 1.19, SE = 0.07, p = .018), and parental mental health problems (OR = 1.30, SE = 0.09, p = .003). Childhood IQ, socioeconomic status, parental education, and parent-child relationships showed no associations with adult ADHD symptom persistence.

conclusionInitial ADHD symptom severity, parental mental health, and childhood comorbidity affect persistence of ADHD symptoms into adulthood. Addressing these areas early may assist in reducing adult ADHD persistence and functioning problems.

Indexed as

Disease ProgressionMental DisordersParentsSeverity of Illness IndexAdultAttention Deficit Disorder with HyperactivityChildChild of Impaired ParentsFemaleFollow-Up StudiesHumansMaleadulthoodattention-deficit/hyperactivity disorder (ADHD)comorbidityfamilyIQ

Identifiers

PMID27806861
PMCPMC5117682
OpenAlexW2515096805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.