Evidence map›Paper›PMID 27806669›Full record

ArticleStem cells and development2017

Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage.

Ravali Raju, David Chau, Dong Seong Cho, Yonsil Park, Catherine M Verfaillie, Wei-Shou Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells and development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ravali Raju1 Department of Chemical Engineering and Materials Science, University of Minnesota , Minneapolis, Minnesota.
David Chau1 Department of Chemical Engineering and Materials Science, University of Minnesota , Minneapolis, Minnesota.
Dong Seong Cho1 Department of Chemical Engineering and Materials Science, University of Minnesota , Minneapolis, Minnesota.
Yonsil Park1 Department of Chemical Engineering and Materials Science, University of Minnesota , Minneapolis, Minnesota.
Catherine M Verfaillie4 Department of Development and Regeneration, Stem Cell Institute Leuven , KU Leuven, Leuven, Belgium .
Wei-Shou Hu1 Department of Chemical Engineering and Materials Science, University of Minnesota , Minneapolis, Minnesota.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The differentiation of human pluripotent stem cells toward the hepatocyte lineage can potentially provide an unlimited source of functional hepatocytes for transplantation and extracorporeal bioartificial liver applications. It is anticipated that the quantities of cells needed for these applications will be in the order of 10

Indexed as

Cell DifferentiationCell LineageBiomarkersCell LineCell ProliferationFlow CytometryGene Expression ProfilingHumansLiverPhenotypeRNA, MessengerStem CellsBiomarkersRNA, Messengerdifferentiationembryonic stem cellsgene expressiongenomicshepatic

Identifiers

PMID27806669
PMCPMC5972777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.