Evidence map›Paper›PMID 27806272›Full record

ArticleBiophysical journal2016

Allosteric Signaling Is Bidirectional in an Outer-Membrane Transport Protein.

Arthur Sikora, Benesh Joseph, Morgan Matson, Jacob R Staley, David S Cafiso

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. GdJournal of the American Chemical Society · 2023
    Article
  3. HDX-MS performed on BtuB inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. Chemical communications (Cambridge, England) · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Arthur SikoraDepartment of Chemistry and Center for Membrane Biology, University of Virginia, Charlottesville, Virginia.
Benesh JosephInstitute of Physical and Theoretical Chemistry and Center for Biomolecular Magnetic Resonance, University of Frankfurt, Frankfurt am Main, Germany.
Morgan MatsonDepartment of Chemistry and Center for Membrane Biology, University of Virginia, Charlottesville, Virginia.
Jacob R StaleyDepartment of Chemistry and Center for Membrane Biology, University of Virginia, Charlottesville, Virginia.
David S CafisoDepartment of Chemistry and Center for Membrane Biology, University of Virginia, Charlottesville, Virginia. Electronic address: cafiso@virginia.edu.
University of Virginia · USGoethe University Frankfurt · DE

Funding

MOLECULAR MECHANISMS OF MEMBRANE TRANSPORTR01GM035215 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI DAVID S CAFISO · 1985 to 2026
$7.3M
NIGMS NIH HHS R01 GM035215
6 · The paper itself

Abstract

In BtuB, the Escherichia coli TonB-dependent transporter for vitamin B

Indexed as

Signal TransductionAllosteric RegulationBacterial Outer Membrane ProteinsBacterial ProteinsBiological TransportCalciumCell MembraneEscherichia coliEscherichia coli ProteinsExtracellular SpaceMembrane ProteinsMembrane Transport ProteinsModels, MolecularProtein ConformationSpin LabelsVitamin B 12Bacterial Outer Membrane ProteinsBacterial ProteinsBtuB protein, E coliCalciumEscherichia coli ProteinsMembrane ProteinsMembrane Transport ProteinsSpin LabelstonB protein, BacteriaVitamin B 12

Identifiers

PMID27806272
PMCPMC5103032
OpenAlexW2546784159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.