ArticlePloS one2016
Barriers, Facilitators and Priorities for Implementation of WHO Maternal and Perinatal Health Guidelines in Four Lower-Income Countries: A GREAT Network Research Activity.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Factors influencing the uptake of antenatal care in Uganda: a mixed methods systematic review.BMC pregnancy and childbirth · 2024Pooled it
- How are global health policies transferred to sub-Saharan Africa countries? A systematic critical review of literature.Globalization and health · 2022Pooled it
- Pooled it
- Training in Ultrasound to Determine Gestational Age in Low- and Middle- Income Countries: A Systematic Review.Frontiers in global women's health · 2022Pooled it
- New Antenatal Model in Africa and India (NAMAI) study: implementation research to improve antenatal care using WHO recommendations.Health research policy and systems · 2023Trial
- Implementation and evaluation of a technical support center for the Research to Enhance the Adaptation and Implementation of Health Systems Guidelines in LMICs [RAISE] initiative.Health research policy and systems · 2026Article
- Barriers in managing maternal schistosomiasis: a qualitative study of healthcare providers in Tanzania.International health · 2026Article
- Bridging policy and practice: a scoping review of health system implementation research practice in Ethiopia.Implementation science communications · 2026Review
- Facilitators of, barriers to and strategies for health-system guidance implementation: a critical interpretive synthesis.npj health systems · 2026Review
- Experiences of Health Professionals Regarding Existing Guidelines Used to Manage Obstetric Emergencies in a Rural Area of South Africa: A Qualitative Explorative Study.International journal of environmental research and public health · 2026Article
- Advancing knowledge translation practices to accelerate change in adolescent and youth sexual and reproductive health practice: a scoping review.Health research policy and systems · 2026Article
- Accelerating the Adoption of Best Practice Research in Resuscitation Through Implementation Science: Identifying Gaps and Pathways.Journal of clinical medicine · 2026Review
- Existing practices, gaps and strategies to promote perinatal mental health in Ghana.Frontiers in global women's health · 2026Article
- Challenges and Prospects in Managing Hypertensive Disorders of Pregnancy in Sub-Saharan Africa: A Narrative Review.International journal of women's health · 2026Review
- Perceptions and experiences of the prevention, identification and management of pre-eclampsia and eclampsia: a qualitative evidence synthesis.The Cochrane database of systematic reviews · 2025Article
- Article
- Effectiveness of dissemination strategies of maternal clinical guidelines: A narrative review.African journal of primary health care & family medicine · 2024Review
- The use of positive deviance approach to improve health service delivery and quality of care: a scoping review.BMC health services research · 2024Article
- Exploring variations in the implementation of a health system level policy intervention to improve maternal and child health outcomes in resource limited settings: A qualitative multiple case study from Uganda.PLOS global public health · 2024Article
- Use of the positive deviance approach for healthcare system service improvement: a scoping review protocol.BMJ open · 2023Article
Corrections and comments
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Authors and funding
19 authors at 9 institutions in 7 countries.
Funding
Abstract
backgroundHealth systems often fail to use evidence in clinical practice. In maternal and perinatal health, the majority of maternal, fetal and newborn mortality is preventable through implementing effective interventions. To meet this challenge, WHO's Department of Reproductive Health and Research partnered with the Knowledge Translation Program at St. Michael's Hospital (SMH), University of Toronto, Canada to establish a collaboration on knowledge translation (KT) in maternal and perinatal health, called the GREAT Network (Guideline-driven, Research priorities, Evidence synthesis, Application of evidence, and Transfer of knowledge). We applied a systematic approach incorporating evidence and theory to identifying barriers and facilitators to implementation of WHO maternal heath recommendations in four lower-income countries and to identifying implementation strategies to address these.
methodsWe conducted a mixed-methods study in Myanmar, Uganda, Tanzania and Ethiopia. In each country, stakeholder surveys, focus group discussions and prioritization exercises were used, involving multiple groups of health system stakeholders (including administrators, policymakers, NGOs, professional associations, frontline healthcare providers and researchers).
resultsDespite differences in guideline priorities and contexts, barriers identified across countries were often similar. Health system level factors, including health workforce shortages, and need for strengthened drug and equipment procurement, distribution and management systems, were consistently highlighted as limiting the capacity of providers to deliver high-quality care. Evidence-based health policies to support implementation, and improve the knowledge and skills of healthcare providers were also identified. Stakeholders identified a range of tailored strategies to address local barriers and leverage facilitators.
conclusionThis approach to identifying barriers, facilitators and potential strategies for improving implementation proved feasible in these four lower-income country settings. Further evaluation of the impact of implementing these strategies is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.