Evidence map›Paper›PMID 27805589›Full record

ArticleJournal of visualized experiments : JoVE2016

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents.

Susheil Uthamaraj, Brandon J Tefft, Soumen Jana, Ota Hlinomaz, Manju Kalra, Amir Lerman, Dan Dragomir-Daescu, Gurpreet S Sandhu

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Magnetic Cell Targeting for Cardiovascular Tissue Engineering.Tissue engineering. Part B, Reviews · 2025
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Magnetizable stent-grafts enable endothelial cell capture.Journal of magnetism and magnetic materials · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Susheil UthamarajDivision of Engineering, Mayo Clinic.
Brandon J TefftDepartment of Cardiovascular Diseases, Mayo Clinic.
Soumen JanaDepartment of Cardiovascular Diseases, Mayo Clinic.
Ota HlinomazDepartment of Cardioangiology, ICRC, St. Anne's University Hospital.
Manju KalraDepartment of Vascular Surgery, Mayo Clinic.
Amir LermanDepartment of Cardiovascular Diseases, Mayo Clinic.
Dan Dragomir-DaescuDivision of Engineering, Mayo Clinic; Department of Physiology and Biomedical Engineering, Mayo Clinic.
Gurpreet S SandhuDepartment of Cardiovascular Diseases, Mayo Clinic; sandhu.gurpreet@mayo.edu.
Mayo Clinic in Arizona · USSt. Anne's University Hospital Brno · CZ

Funding

CARDIOVASOLOGYT32HL007111 · NHLBI · MAYO CLINIC ROCHESTER · PI Barry A. Borlaug · 1985 to 2026
$8.7M
NHLBI NIH HHS T32 HL007111
6 · The paper itself

Abstract

Stent-grafts are widely used for the treatment of various conditions such as aortic lesions, aneurysms, emboli due to coronary intervention procedures and perforations in vasculature. Such stent-grafts are manufactured by covering a stent with a polymer membrane. An ideal stent-graft should have a biocompatible stent covered by a porous, thromboresistant, and biocompatible polymer membrane which mimics the extracellular matrix thereby promoting injury site healing. The goal of this protocol is to manufacture a small caliber stent-graft by encapsulating a balloon expandable stent within two layers of electrospun polyurethane nanofibers. Electrospinning of polyurethane has been shown to assist in healing by mimicking native extracellular matrix, thereby promoting endothelialization. Electrospinning polyurethane nanofibers on a slowly rotating mandrel enabled us to precisely control the thickness of the nanofibrous membrane, which is essential to achieve a small caliber balloon expandable stent-graft. Mechanical validation by crimping and expansion of the stent-graft has shown that the nanofibrous polyurethane membrane is sufficiently flexible to crimp and expand while staying patent without showing any signs of tearing or delamination. Furthermore, stent-grafts fabricated using the methods described here are capable of being implanted using a coronary intervention procedure using standard size guide catheters.

Indexed as

Prosthesis DesignStentsAortaEquipment DesignHumansMetalsNanofibersPolyurethanesTransplantsMetalsPolyurethanes

Identifiers

PMID27805589
PMCPMC5092244
OpenAlexW2541822012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.