Evidence map›Paper›PMID 27805200›Full record

ArticleChemical communications (Cambridge, England)2016

Control of bacterial nitrate assimilation by stabilization of G-quadruplex DNA.

Zoë A E Waller, Benjamin J Pinchbeck, Bhovina Seewoodharry Buguth, Timothy G Meadows, David J Richardson, Andrew J Gates

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Transcription activation inEcoSal Plus · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. The Rich World of p53 DNA Binding Targets: The Role of DNA Structure.International journal of molecular sciences · 2019
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zoë A E WallerSchool of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ, UK. z.waller@uea.ac.uk.
Benjamin J Pinchbeck
Bhovina Seewoodharry Buguth
Timothy G Meadows
David J Richardson
Andrew J Gates
Norwich Research Park · GBUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/E021999/1Biotechnology and Biological Sciences Research Council BB/H012796/1
6 · The paper itself

Abstract

Here we present a chemical-biology study in the model soil bacterium Paracoccus denitrificans, where we show ligand-specific control of nitrate assimilation. Stabilization of a G-quadruplex in the promoter region of the nas genes, encoding the assimilatory nitrate/nitrite reductase system, is achieved using known quadruplex ligands and results in attenuation of gene transcription.

Indexed as

G-QuadruplexesDNA, BacterialLigandsNitratesParacoccus denitrificansDNA, BacterialLigandsNitrates

Identifiers

PMID27805200
PMCPMC5123632
OpenAlexW2546612288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.