ArticleScientific reports2016
The Seminal fluid proteome of the polyandrous Red junglefowl offers insights into the molecular basis of fertility, reproductive ageing and domestication.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 56 citations in OpenAlex.
- Current Applications and Future Prospects of High-ThroughputAnimals : an open access journal from MDPI · 2026Review
- Experimental Evidence That Prenatal and Postnatal Developmental Stress Affects the Adult Seminal Fluid Proteome in a Precocial Bird.Molecular ecology · 2026Article
- Rooster Behavior and Laying Breeder Performance in Natural Mating Cages as a Function of Different Rearing Management.Animals : an open access journal from MDPI · 2025Article
- The Omics Revolution in Understanding Chicken Reproduction: A Comprehensive Review.Current issues in molecular biology · 2024Review
- Genotype-by-environment interactions influence the composition of theProceedings. Biological sciences · 2023Article
- Separating the effects of paternal age and mating history: Evidence for sex-specific paternal effect in eastern mosquitofish.Evolution; international journal of organic evolution · 2022Article
- Article
- Identification and Structure Prediction of Human Septin-4 as a Biomarker for Diagnosis of Asthenozoospermic Infertile Patients-Critical Finding Toward Personalized Medicine.Frontiers in medicine · 2021Article
- Pronounced Postmating Response in the Drosophila Female Reproductive Tract Fluid Proteome.Molecular & cellular proteomics : MCP · 2021Article
- Seminal fluid and accessory male investment in sperm competition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Functional Aspects of Seminal Plasma in Bird Reproduction.International journal of molecular sciences · 2020Review
- Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable inProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Seminal Plasma Proteome as an Indicator of Sperm Dysfunction and Low Sperm Motility in Chickens.Molecular & cellular proteomics : MCP · 2020Article
- Molecular Diversification of the Seminal Fluid Proteome in a Recently Diverged Passerine Species Pair.Molecular biology and evolution · 2020Article
- BMP signaling inhibition inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Divergent allocation of sperm and the seminal proteome along a competition gradient inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- The seminal acrosin-inhibitor ClTI1/SPINK2 is a fertility-associated marker in the chicken.Molecular reproduction and development · 2019Article
- Female novelty and male status dynamically modulate ejaculate expenditure and seminal fluid proteome over successive matings in red junglefowl.Scientific reports · 2019Article
- Stable-protein Pair Analysis as A Novel Strategy to Identify Proteomic Signatures: Application To Seminal Plasma From Infertile Patients.Molecular & cellular proteomics : MCP · 2019Article
- Proteins, Transcripts, and Genetic Architecture of Seminal Fluid and Sperm in the MosquitoMolecular & cellular proteomics : MCP · 2019Article
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seminal fluid proteins (SFPs) are emerging as fundamental contributors to sexual selection given their role in post-mating reproductive events, particularly in polyandrous species where the ejaculates of different males compete for fertilisation. SFP identification however remains taxonomically limited and little is known about avian SFPs, despite extensive work on sexual selection in birds. We characterize the SF proteome of the polyandrous Red junglefowl, Gallus gallus, the wild species that gave rise to the domestic chicken. We identify 1,141 SFPs, including proteins involved in immunity and antimicrobial defences, sperm maturation, and fertilisation, revealing a functionally complex SF proteome. This includes a predominant contribution of blood plasma proteins that is conserved with human SF. By comparing the proteome of young and old males with fast or slow sperm velocity in a balanced design, we identify proteins associated with ageing and sperm velocity, and show that old males that retain high sperm velocity have distinct proteome characteristics. SFP comparisons with domestic chickens revealed both qualitative and quantitative differences likely associated with domestication and artificial selection. Collectively, these results shed light onto the functional complexity of avian SF, and provide a platform for molecular studies of fertility, reproductive ageing, and domestication.
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