Evidence map›Paper›PMID 27804289›Full record

ArticleJournal of the American Chemical Society2016

Ligand Promoted meta-C-H Chlorination of Anilines and Phenols.

Hang Shi, Peng Wang, Shin Suzuki, Marcus E Farmer, Jin-Quan Yu

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Chemical science · 2026
    Article
  2. Article
  3. From Mono-Accounts of chemical research · 2025
    Review
  4. NBS-Mediated C(spInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Article
  7. Pd(ii)-catalyzedChemical science · 2022
    Article
  8. Review
  9. Article
  10. meta-Selective C-H Arylation of Fluoroarenes and Simple Arenes.Angewandte Chemie (International ed. in English) · 2020
    Article
  11. Journal of the American Chemical Society · 2019
    Article
  12. Article
  13. Article
  14. Review
  15. Palladium CatalyzedACS catalysis · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Ligand-Promoted meta-C-H Functionalization of Benzylamines.Angewandte Chemie (International ed. in English) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hang ShiDepartment of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Peng WangDepartment of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Shin SuzukiDepartment of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Marcus E FarmerDepartment of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Jin-Quan YuDepartment of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Funding

Catalyst-Controlled Site-Selective C-H Functionalizations of Arenes and HeteroarenesR01GM102265 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI YU, JIN-QUAN · 2012 to 2023
$4.6M
NIGMS NIH HHS R01 GM102265
6 · The paper itself

Abstract

Pd-catalyzed meta-C-H chlorination of anilines and phenols is developed using norbornene as the mediator. Heterocycles, including indole, thiophene, and indazole, are tolerated. The identification of a new pyridone-based ligand is crucial for the success of this meta-C-H chlorination reaction. Subsequent diverse transformations of the chlorinated products demonstrate the versatility of meta-C-H chlorination.

Indexed as

Aniline CompoundsCatalysisHalogenationHydrocarbons, ChlorinatedLigandsMolecular StructurePalladiumPhenolsAniline CompoundsHydrocarbons, ChlorinatedLigandsPalladiumPhenols

Identifiers

PMID27804289
PMCPMC5512287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.