Evidence map›Paper›PMID 27804177›Full record

ArticleStatistics in medicine2017

Targeted use of growth mixture modeling: a learning perspective.

Booil Jo, Robert L Findling, Chen-Pin Wang, Trevor J Hastie, Eric A Youngstrom, L Eugene Arnold, Mary A Fristad, Sarah McCue Horwitz

Abstract read
In one paragraph

Article in Statistics in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  11. Characterizing the post-traumatic growth trajectory in gastric cancer survivors: a population-based longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  12. Article
  13. Article
  14. Facilitating Growth Mixture Model Convergence in Preventive Interventions.Prevention science : the official journal of the Society for Prevention Research · 2023
    Review
  15. Semiparametric Latent Class Analysis of Recurrent Event Data.Journal of the Royal Statistical Society. Series B, Statistical methodology · 2022
    Article
  16. Article
  17. Observational
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Booil JoStanford University, Stanford, CA, U.S.A.
Robert L FindlingJohns Hopkins University, Baltimore, MD, U.S.A.
Chen-Pin WangUniversity of Texas Health Science Center, San Antonio, TX, U.S.A.
Trevor J HastieStanford University, Stanford, CA, U.S.A.
Eric A YoungstromUniversity of North Carolina, Chapel Hill, NC, U.S.A.
L Eugene ArnoldOhio State University, Columbus, OH, U.S.A.
Mary A FristadOhio State University, Columbus, OH, U.S.A.
Sarah McCue HorwitzNew York University, New York, NY, U.S.A.

Funding

Longitudinal Assessment of Manic SymptomsR01MH073967 · NIMH · JOHNS HOPKINS UNIVERSITY · PI FINDLING, ROBERT L · 2005 to 2016
$11.4M
Longitudinal Assessment of Manic Symptoms (LAMS)R01MH073953 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS, PHILLIPS, MARY LOUISE · 2005 to 2016
$8.7M
Translational Neuroscience CoreU54HD079123 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI FATEMI, S. ALI, SCHLAGGAR, BRADLEY L · 2014 to 2019
$7.9M
Longitudinal Assessment of Manic Symptoms (LAMS)R01MH073816 · NIMH · CINCINNATI CHILDRENS HOSP MED CTR · PI HOLLAND, SCOTT K. · 2005 to 2016
$5.9M
Longitudinal Assessment of Manic Symptoms (LAMS) StudyR01MH073801 · NIMH · OHIO STATE UNIVERSITY · PI FRISTAD, MARY A · 2005 to 2016
$5.9M
Heterogeneity in Prevention Intervention Effects On Substance Use: A Latent VariaR01DA031698 · NIDA · STANFORD UNIVERSITY · PI JO, BOOIL · 2012 to 2014
$652k
NICHD NIH HHS U54 HD079123NIDA NIH HHS R01 DA031698NIMH NIH HHS R01 MH073801NIMH NIH HHS R01 MH073816NIMH NIH HHS R01 MH073953NIMH NIH HHS R01 MH073967
6 · The paper itself

Abstract

From the statistical learning perspective, this paper shows a new direction for the use of growth mixture modeling (GMM), a method of identifying latent subpopulations that manifest heterogeneous outcome trajectories. In the proposed approach, we utilize the benefits of the conventional use of GMM for the purpose of generating potential candidate models based on empirical model fitting, which can be viewed as unsupervised learning. We then evaluate candidate GMM models on the basis of a direct measure of success; how well the trajectory types are predicted by clinically and demographically relevant baseline features, which can be viewed as supervised learning. We examine the proposed approach focusing on a particular utility of latent trajectory classes, as outcomes that can be used as valid prediction targets in clinical prognostic models. Our approach is illustrated using data from the Longitudinal Assessment of Manic Symptoms study. Copyright © 2016 John Wiley & Sons, Ltd.

Indexed as

Longitudinal StudiesMachine LearningModels, StatisticalSupervised Machine LearningBipolar DisorderHumansPatient Outcome AssessmentPrognosisReproducibility of Resultsearly predictiongrowth mixture modelinglatent trajectory classsensitivityspecificitysupervised learningunsupervised learning

Identifiers

PMID27804177
PMCPMC5217165

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.