ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Long-term prognostic value of coronary artery calcium scanning, coronary computed tomographic angiography and stress myocardial perfusion imaging in patients with suspected coronary artery disease.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Update of the Brazilian Guideline on Nuclear Cardiology - 2020.Arquivos brasileiros de cardiologia · 2020Guideline
- Prognostic value of myocardial flow reserve by PET imaging in patients with suspected coronary artery disease: A systematic review and meta-analysis.International journal of cardiology. Heart & vasculature · 2025Article
- Impact on cardiovascular outcome of coronary revascularization-induced changes in ischemic perfusion defect and myocardial flow reserve.European journal of nuclear medicine and molecular imaging · 2024Article
- Combined evaluation of CAC score and myocardial perfusion imaging in patients at risk of cardiovascular disease: where are we and what do the data say.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Myocardial perfusion reserve by CZT cameras: A journey inside coronary microvascular circulation. Is it time to leave yet?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- The addition of coronary artery calcium to myocardial perfusion: Double or nothing?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Prediction of outcome byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Epicardial fat volume, an independent risk factor for major adverse cardiovascular events, had an incremental prognostic value to myocardial perfusion imaging in Chinese populations with suspected or known coronary artery disease with a normal left ventricular ejection fraction.Frontiers in cardiovascular medicine · 2023Article
- Regional myocardial perfusion imaging in predicting vessel-related outcome: interplay between the perfusion results and angiographic findings.European journal of nuclear medicine and molecular imaging · 2022Article
- The Diagnostic and Prognostic Value of Coronary Calcium Scoring in Stable Chest Pain Patients: A Narrative Review.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2022Review
- ASNC's thoughts on the AHA/ACC chest pain guidelines.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- The often-overlooked elements of #PatientFirst imaging: Focus on optimal quality, including up-to-date protocols and equipment.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Reduction of cardiac imaging tests during the COVID-19 pandemic: The case of Italy. Findings from the IAEA Non-invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID).International journal of cardiology · 2021Article
- Computed tomography calls out nuclear imaging in its field: It doesn't matter how you are searching but what you are looking for.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Relationship between coronary artery calcification and myocardial ischemia on computed tomography myocardial perfusion in patients with stable chest pain.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- ASNC stands for #PatientFirst imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Spatially Weighted Coronary Artery Calcium Score and Coronary Heart Disease Events in the Multi-Ethnic Study of Atherosclerosis.Circulation. Cardiovascular imaging · 2021Article
- Combined evaluation of regional coronary artery calcium and myocardial perfusion byEuropean journal of nuclear medicine and molecular imaging · 2020Article
- The machine learning approach: Artificial intelligence is coming to support critical clinical thinking.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Coronary vascular age: An alternate means for predicting stress-induced myocardial ischemia in patients with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe compared the long-term prognostic value of coronary artery calcium (CAC) scanning, coronary computed tomographic angiography (CCTA), and stress single-photon emission computed tomography myocardial perfusion imaging (MPI) in patients with suspected coronary artery disease (CAD). METHODS AND
resultsA total of 164 patients were studied. CAC score was measured according to the Agatston method and patients were categorized into 3 groups (0, 1-300, and >300). The following events were recorded: cardiac death, nonfatal infarction, and unstable angina requiring revascularization. Follow-up was 95% complete during a mean period of 82 ± 34 months. During follow-up, 22 events occurred (14% cumulative event rate). Event-free survival decreased with worsening of CAC score category (P < .001) and it was worse (P < .001) in patients with significant CAD (≥50% stenosis) and in those with stress-induced ischemia (summed difference score >2). At multivariable analysis, CAC (P = .001) and ischemia (P = .012) were independent predictors of events. MPI data added prognostic information to a model including clinical variables, CAC and CCTA findings, increasing the global Chi-square from 36.2 to 41.9 (P = .013). The decision curve analyses in patients with CAC score >0 indicate that the prognostic model including MPI resulted in a higher net benefit across a wide range of decision threshold probabilities.
conclusionsCAC and MPI, but not CCTA, are independent predictors of cardiac events. Stress MPI appears to improve risk stratification over clinical variables, CAC scanning and CCTA findings.
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